Substance P (6-11), glp(6)-iodo-tyr(8)-

Base Information

Chemical Name:Substance P (6-11), glp(6)-iodo-tyr(8)-
CAS No.:70082-71-2
Molecular Formula:C₃₆H₄₉N₇O₈S
Molecular Weight:739.893
Hs Code.:
DSSTox Substance ID:DTXSID50220357
Nikkaji Number:J458.691C
Wikidata:Q83097557
Mol file:70082-71-2.mol

Synonyms:6-Glp-8-iodo-Tyr-substance P (6-11);GIT-SP(6-11);substance P (6-11), Glp(6)-iodo-Tyr(8)-;substance P (6-11), pyroglutamyl(6)-iodo-tyrosine(8)-

Suppliers and Price of Substance P (6-11), glp(6)-iodo-tyr(8)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Substance P (6-11), glp(6)-iodo-tyr(8)-

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:1239.5°C at 760 mmHg
Flash Point:703.4°C
PSA：263.22000
Density:1.278g/cm³
LogP:2.77950
XLogP3:1.7
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:20
Exact Mass:739.33633272
Heavy Atom Count:52
Complexity:1240

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C3CCC(=O)N3
Isomeric SMILES:CC(C)C[C@@H](C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)CNC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H]3CCC(=O)N3

Technology Process of Substance P (6-11), glp(6)-iodo-tyr(8)-

There total 7 articles about Substance P (6-11), glp(6)-iodo-tyr(8)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 70082-71-2
p-Glu-Phe-Tyr-Gly-Leu-Met-NH₂

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) Et₃N, diphenylphosphoryl azide (DPPA), 2.) Et₃N / 1.) DMF, 0 deg, 20 min., 2.) DMF, a) 0 deg, 3 h, b) RT, 48 h

2: 87 percent / hydrazine hydrate / methanol / 144 h

3: NaNO₂, HCl / acetic acid / 0.25 h / 0 °C

4: 2.6 g / Et₃N / dimethylformamide / 144 h / 0 °C

5: 70 percent / HCl / dioxane / 0.5 h / Ambient temperature

6: 1.) Et₃N, diphenylphosphoryl azide (DPPA), 2.) Et₃N / 1.) DMF, 0 deg, 30 min., 2.) DMF, a) 0 deg, 3 h, b) RT, 72 h

With hydrogenchloride; diphenylphosphoranyl azide; hydrazine hydrate; triethylamine; sodium nitrite; In 1,4-dioxane; methanol; acetic acid; N,N-dimethyl-formamide;

Reference yield:

: 4583-09-9
Boc-Phe-Tyr-Gly-Leu-Met-NH₂

: 70082-71-2
p-Glu-Phe-Tyr-Gly-Leu-Met-NH₂

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / HCl / dioxane / 0.5 h / Ambient temperature

2: 1.) Et₃N, diphenylphosphoryl azide (DPPA), 2.) Et₃N / 1.) DMF, 0 deg, 30 min., 2.) DMF, a) 0 deg, 3 h, b) RT, 72 h

With hydrogenchloride; diphenylphosphoranyl azide; triethylamine; In 1,4-dioxane;

Reference yield:

: 3417-91-2
L-tyrosine methyl ester HCl

: 70082-71-2
p-Glu-Phe-Tyr-Gly-Leu-Met-NH₂

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) Et₃N, diphenylphosphoryl azide (DPPA), 2.) Et₃N / 1.) DMF, 0 deg, 20 min., 2.) DMF, a) 0 deg, 3 h, b) RT, 48 h

2: 87 percent / hydrazine hydrate / methanol / 144 h

3: NaNO₂, HCl / acetic acid / 0.25 h / 0 °C

4: 2.6 g / Et₃N / dimethylformamide / 144 h / 0 °C

5: 70 percent / HCl / dioxane / 0.5 h / Ambient temperature

6: 1.) Et₃N, diphenylphosphoryl azide (DPPA), 2.) Et₃N / 1.) DMF, 0 deg, 30 min., 2.) DMF, a) 0 deg, 3 h, b) RT, 72 h

With hydrogenchloride; diphenylphosphoranyl azide; hydrazine hydrate; triethylamine; sodium nitrite; In 1,4-dioxane; methanol; acetic acid; N,N-dimethyl-formamide;