2,3-Pentanedione, 5-hydroxy- (9CI)

Base Information

Chemical Name:2,3-Pentanedione, 5-hydroxy- (9CI)
CAS No.:142937-56-2
Molecular Formula:C5H8 O3
Molecular Weight:116.117
Hs Code.:
Mol file:142937-56-2.mol

Synonyms:Laurencione

Suppliers and Price of 2,3-Pentanedione, 5-hydroxy- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 12 raw suppliers

Chemical Property of 2,3-Pentanedione, 5-hydroxy- (9CI)

Chemical Property:

PSA：54.37000
LogP:-0.47310

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

General Description **2,3-Pentanedione, 5-hydroxy- (9CI)**, also known as **laurencione**, is a labile dihydro-3(2H)-furanone derivative originally isolated from the red alga *Laurencia spectabilis*. It is also identified as a bacterial metabolite derived from 1-deoxy-D-threo-pentulose, formed via condensation of (hydroxyethyl)thiamin with D-glyceraldehyde in *Escherichia coli* and *Klebsiella planticola*. 2,3-Pentanedione, 5-hydroxy- (9CI) is synthesized through acid-catalyzed hydrolysis of intermediates such as 3,3-dimethoxy-2-hydroxy-2-methyltetrahydrofuran. Laurencione exhibits structural and functional relevance as an α-dicarbonyl compound, with potential flavor-related properties.

Technology Process of 2,3-Pentanedione, 5-hydroxy- (9CI)

There total 15 articles about 2,3-Pentanedione, 5-hydroxy- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 195197-90-1
5-((tert-butyldimethylsilyl)oxy)pentane-2,3-dione

: 142937-56-2
1,4-dideoxypentodiulose

Guidance literature:: With hydrogen fluoride; In acetonitrile; for 0.75h;
DOI:10.1139/v97-113

Reference yield:

: 10229-10-4
pent-3-yn-1-ol

: 142937-56-2
1,4-dideoxypentodiulose

Guidance literature:: Multi-step reaction with 5 steps

1: 92.5 percent / imidazole / dimethylformamide / Ambient temperature

2: 99 percent / H₂, quinoline / Lindlar catalyst / ethyl acetate / 759.8 Torr

3: 99 percent / aq. 4-methylmorpholine-N-oxide, 4percent aq. OsO₄ / 2-methyl-propan-2-ol; tetrahydrofuran / 5 h / Ambient temperature

4: 95 percent / aq. 2,2,6,6-tetramethyl-1-piperidinyloxy, KBr, aq. NaHCO₃, aq. NaOCl / CH₂Cl₂ / 0.17 h

5: 80 percent / 49percent aq. HF / acetonitrile / 0.75 h

With 1H-imidazole; quinoline; 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; osmium(VIII) oxide; hydrogen fluoride; hydrogen; sodium hydrogencarbonate; 4-methylmorpholine N-oxide; potassium bromide; Lindlar's catalyst; In tetrahydrofuran; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;
DOI:10.1139/v97-113

Reference yield:

: 104066-69-5
tert-butyldimethylsilyl(3-pentynyloxy)silane

: 142937-56-2
1,4-dideoxypentodiulose

Guidance literature:: Multi-step reaction with 4 steps

1: 99 percent / H₂, quinoline / Lindlar catalyst / ethyl acetate / 759.8 Torr

2: 99 percent / aq. 4-methylmorpholine-N-oxide, 4percent aq. OsO₄ / 2-methyl-propan-2-ol; tetrahydrofuran / 5 h / Ambient temperature

3: 95 percent / aq. 2,2,6,6-tetramethyl-1-piperidinyloxy, KBr, aq. NaHCO₃, aq. NaOCl / CH₂Cl₂ / 0.17 h

4: 80 percent / 49percent aq. HF / acetonitrile / 0.75 h

With quinoline; 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; osmium(VIII) oxide; hydrogen fluoride; hydrogen; sodium hydrogencarbonate; 4-methylmorpholine N-oxide; potassium bromide; Lindlar's catalyst; In tetrahydrofuran; dichloromethane; ethyl acetate; acetonitrile; tert-butyl alcohol;
DOI:10.1139/v97-113