Technology Process of Phosphoric acid, 1-(4-chlorophenyl)-2-(ethylthio)ethenyl diethyl ester
There total 3 articles about Phosphoric acid, 1-(4-chlorophenyl)-2-(ethylthio)ethenyl diethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-(4-chlorophenyl)ethanonyl ethyl sulfide;
With
lithium hexamethyldisilazane;
In
tetrahydrofuran; ethylbenzene;
at -78 ℃;
for 0.5h;
Inert atmosphere;
diethyl chlorophosphate;
In
tetrahydrofuran; ethylbenzene;
at -78 - 20 ℃;
for 0.5h;
Inert atmosphere;
DOI:10.1002/ejoc.201201422
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium methylate / methanol / 0.08 h / Inert atmosphere
1.2: Inert atmosphere
2.1: lithium hexamethyldisilazane / tetrahydrofuran; ethylbenzene / 0.5 h / -78 °C / Inert atmosphere
2.2: 0.5 h / -78 - 20 °C / Inert atmosphere
With
sodium methylate; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol; ethylbenzene;
DOI:10.1002/ejoc.201201422
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: copper(I) bromide / ethanol / 60 °C / Inert atmosphere
2.1: sodium methylate / methanol / 0.08 h / Inert atmosphere
2.2: Inert atmosphere
3.1: lithium hexamethyldisilazane / tetrahydrofuran; ethylbenzene / 0.5 h / -78 °C / Inert atmosphere
3.2: 0.5 h / -78 - 20 °C / Inert atmosphere
With
sodium methylate; copper(I) bromide; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol; ethanol; ethylbenzene;
DOI:10.1002/ejoc.201201422
