12beta,13alpha-Dihydrojervine-11alpha-ol

Base Information

Chemical Name:12beta,13alpha-Dihydrojervine-11alpha-ol
CAS No.:73825-59-9
Molecular Formula:C26H40NO3
Molecular Weight:414.67
Hs Code.:

Synonyms:12beta,13alpha-Dihydrojervine-11alpha-ol;12-beta,13-alpha-Dihydrojervine-11-alpha-ol;11-Deoxo-12-beta,13-alpha-dihydro-11-alpha-hydroxyjervine;JERVINE, 11-DEOXO-12-beta,13-alpha-DIHYDRO-11-alpha-HYDROXY-;73825-59-9;C26-H40-N-O3;Veratraman-3,11-diol, 17,23-epoxy-12,13-dihydro-, (3.beta.,11.alpha.,12.beta.,13.beta.,23.beta.)-;LS-86885

Suppliers and Price of 12beta,13alpha-Dihydrojervine-11alpha-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 12beta,13alpha-Dihydrojervine-11alpha-ol

Chemical Property:

Vapor Pressure:9.78E-16mmHg at 25°C
Refractive Index:1.6000 (estimate)
Boiling Point:577.4°C at 760 mmHg
PKA:14.73±0.70(Predicted)
Flash Point:303°C
PSA：61.72000
Density:1.17g/cm³
LogP:4.23730
XLogP3:3.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:429.32429423
Heavy Atom Count:31
Complexity:768

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(C4C3C)O)C)O)C)NC1
Isomeric SMILES:C[C@H]1C[C@@H]2[C@H]([C@H](C3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5[C@@H]([C@@H]4[C@H]3C)O)C)O)C)NC1

Technology Process of 12beta,13alpha-Dihydrojervine-11alpha-ol

There total 2 articles about 12beta,13alpha-Dihydrojervine-11alpha-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21842-58-0,67321-65-7
(22Ξ,23S)-3β-hydroxy-17,23-epoxy-(17αH)-veratr-5-en-11-one

: 14425-20-8,14425-39-9,51340-26-2,73825-59-9
22,27-Imino-17,23-oxido-Δ⁵-jerven-3β,11β-diol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 10h; Heating;
DOI:10.1016/S0040-4020(01)82558-8

Reference yield:

: 14425-20-8,14425-39-9,51340-26-2,73825-59-9
17,23-epoxy-veratr-5-ene-3,11-diol

Guidance literature:: aus Jervin-11β-ol(4) mit Li/CH3CH2NH2;
DOI:10.1246/bcsj.46.3536

Reference yield:

: 14425-20-8,14425-39-9,51340-26-2,73825-59-9
(22Ξ,23S)-17,23-epoxy-(17αH)-veratr-5-ene-3β,11α-diol

: 14425-29-7,24508-94-9
22,27-Imino-17,23-oxido-5β-jervan-3α-ol-11-on

Guidance literature:: Multi-step reaction with 4 steps

1: toluene / 9 h / Heating; Al(iPrO)3, cyclohexanone

2: H₂, KOH / Pd-C / ethanol / 0.75 h / Ambient temperature

3: CrO₃, H₂SO₄ / dimethylformamide / 48 h / Ambient temperature

4: H₂, KOH / Pt / ethanol / 4 h / Ambient temperature

With chromium(VI) oxide; potassium hydroxide; sulfuric acid; hydrogen; palladium on activated charcoal; platinum; In ethanol; N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0040-4020(01)82558-8