5-Pyrimidinecarboxamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxy-2-propyl-, fumarate, (2:3)

Base Information

Chemical Name:5-Pyrimidinecarboxamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxy-2-propyl-, fumarate, (2:3)
CAS No.:72412-13-6
Molecular Formula:3C₄H₄O₄*2C₁₆H₂₆N₄O₂
Molecular Weight:961.036
Hs Code.:
Mol file:72412-13-6.mol

Synonyms:72412-13-6;5-Pyrimidinecarboxamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxy-2-propyl-, fumarate, (2:3);C16H26N4O2.3/2C4H4O4;LS-134819;C16-H26-N4-O2.3/2C4-H4-O4

Suppliers and Price of 5-Pyrimidinecarboxamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxy-2-propyl-, fumarate, (2:3)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-((1-ETHYL-2-PYRROLIDINYL)METHYL)-4-METHOXY-2-PROPYL-5-PYRIMIDINE CARBOXAMIDE FUMARATE 95.00%
5MG
$ 495.41

Total 0 raw suppliers

Chemical Property of 5-Pyrimidinecarboxamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxy-2-propyl-, fumarate, (2:3)

Chemical Property:

Vapor Pressure:9.64E-09mmHg at 25°C
Boiling Point:462.7°C at 760 mmHg
Flash Point:233.6°C
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:22
Rotatable Bond Count:20
Exact Mass:960.44402798
Heavy Atom Count:68
Complexity:472

Purity/Quality:: N-((1-ETHYL-2-PYRROLIDINYL)METHYL)-4-METHOXY-2-PROPYL-5-PYRIMIDINE CARBOXAMIDE FUMARATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCC1=NC=C(C(=N1)OC)C(=O)NCC2CCCN2CC.CCCC1=NC=C(C(=N1)OC)C(=O)NCC2CCCN2CC.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O
Isomeric SMILES:CCCC1=NC=C(C(=N1)OC)C(=O)NCC2N(CCC2)CC.CCCC1=NC=C(C(=N1)OC)C(=O)NCC2N(CCC2)CC.C(=C/C(=O)O)\C(=O)O.C(=C/C(=O)O)\C(=O)O.C(=C/C(=O)O)\C(=O)O

Technology Process of 5-Pyrimidinecarboxamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxy-2-propyl-, fumarate, (2:3)

There total 4 articles about 5-Pyrimidinecarboxamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-4-methoxy-2-propyl-, fumarate, (2:3) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 72419-29-5
4-Hydroxy-2-propyl-pyrimidine-5-carboxylic acid ethyl ester

: 72412-13-6,84332-32-1
4-Methoxy-2-propyl-pyrimidine-5-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide; compound with (E)-but-2-enedioic acid

Guidance literature:: Multi-step reaction with 4 steps

1: phosphorus oxychloride / triethylamine / 0.5 h / 40 °C

2: 73 percent / sodium / Ambient temperature

3: NaOH / methanol; H₂O / 1 h / 65 °C

4: 1.) triethylamine, ethylchloroformate / 1.) THF, 0 deg C, 30 min, 2.) room temp. overnight

With sodium hydroxide; sodium; chloroformic acid ethyl ester; triethylamine; trichlorophosphate; In methanol; water; triethylamine;

Reference yield:

: 72419-32-0
4-Chloro-2-propyl-pyrimidine-5-carboxylic acid ethyl ester

: 72412-13-6,84332-32-1
4-Methoxy-2-propyl-pyrimidine-5-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide; compound with (E)-but-2-enedioic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / sodium / Ambient temperature

2: NaOH / methanol; H₂O / 1 h / 65 °C

3: 1.) triethylamine, ethylchloroformate / 1.) THF, 0 deg C, 30 min, 2.) room temp. overnight

With sodium hydroxide; sodium; chloroformic acid ethyl ester; triethylamine; In methanol; water;

Reference yield:

: 72411-78-0
4-methoxy-2-propyl-pyrimidine-5-carboxylic acid methyl ester

: 72412-13-6,84332-32-1
4-Methoxy-2-propyl-pyrimidine-5-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide; compound with (E)-but-2-enedioic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / methanol; H₂O / 1 h / 65 °C

2: 1.) triethylamine, ethylchloroformate / 1.) THF, 0 deg C, 30 min, 2.) room temp. overnight

With sodium hydroxide; chloroformic acid ethyl ester; triethylamine; In methanol; water;