4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenyl((((4-(propylamino)benzoyl)hydrazono)acetyl)amino)acetyl)amino)-, (2S-(2-alpha,5-alpha,6-beta(S*)))-

Base Information

Chemical Name:4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenyl((((4-(propylamino)benzoyl)hydrazono)acetyl)amino)acetyl)amino)-, (2S-(2-alpha,5-alpha,6-beta(S*)))-
CAS No.:143667-46-3
Molecular Formula:C₂₈H₃₂N₆O₆S
Molecular Weight:580.665
Hs Code.:

4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenyl((((4-(propylamino)benzoyl)hydrazono)acetyl)amino)acetyl)amino)-, (2S-(2-alpha,5-alpha,6-beta(S*)))-

Synonyms:143667-46-3;4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenyl((((4-(propylamino)benzoyl)hydrazono)acetyl)amino)acetyl)amino)-, (2S-(2-alpha,5-alpha,6-beta(S*)))-;LS-149856

Suppliers and Price of 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenyl((((4-(propylamino)benzoyl)hydrazono)acetyl)amino)acetyl)amino)-, (2S-(2-alpha,5-alpha,6-beta(S*)))-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenyl((((4-(propylamino)benzoyl)hydrazono)acetyl)amino)acetyl)amino)-, (2S-(2-alpha,5-alpha,6-beta(S*)))-

Chemical Property:

Density:1.438g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:11
Exact Mass:580.21040394
Heavy Atom Count:41
Complexity:1040

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCNC1=CC=C(C=C1)C(=O)NN=CC(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O
Isomeric SMILES:CCCNC1=CC=C(C=C1)C(=O)N/N=C/C(=O)NC(C2=CC=CC=C2)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)O

Technology Process of 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenyl((((4-(propylamino)benzoyl)hydrazono)acetyl)amino)acetyl)amino)-, (2S-(2-alpha,5-alpha,6-beta(S*)))-

There total 2 articles about 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenyl((((4-(propylamino)benzoyl)hydrazono)acetyl)amino)acetyl)amino)-, (2S-(2-alpha,5-alpha,6-beta(S*)))- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 143667-37-2
4-Propylamino-benzoic acid hydrazide

: 143667-46-3
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenyl-2-{2-[(4-propylamino-benzoyl)-hydrazono]-acetylamino}-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂O / 0.08 h / Heating

2: 1.) N-methylmorpholine, 4-dimethylaminopyridine, isobutyl chloroformate, 2.) TEM / 1.) DMF, -15 deg C, 30 min, 2.) THF, water, a) -20 deg C, 1 h, b) r.t., 2 h

With 4-methyl-morpholine; dmap; isobutyl chloroformate; In water;

Reference yield:

: 143667-30-5
[(4-Propylamino-benzoyl)-hydrazono]-acetic acid

: 33993-48-5
ampicillin

: 143667-46-3
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenyl-2-{2-[(4-propylamino-benzoyl)-hydrazono]-acetylamino}-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid

Guidance literature:: With 4-methyl-morpholine; dmap; isobutyl chloroformate; Multistep reaction; 1.) DMF, -15 deg C, 30 min, 2.) THF, water, a) -20 deg C, 1 h, b) r.t., 2 h;