Bis[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]diazene

Base Information

• Chemical Name: Bis[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]diazene
• CAS No.: 65171-20-2
• Molecular Formula: C₁₄F₁₄N₂
• Molecular Weight: 462.145
• DSSTox Substance ID: DTXSID20983745
• Mol file: 65171-20-2.mol

Synonyms:65171-20-2;Bis[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]diazene;DTXSID20983745

Chemical Property of Bis[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]diazene

Chemical Property:

• XLogP3: 6.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 16
• Rotatable Bond Count: 2
• Exact Mass: 461.9837923
• Heavy Atom Count: 30
• Complexity: 539

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1(=C(C(=C(C(=C1F)F)N=NC2=C(C(=C(C(=C2F)F)C(F)(F)F)F)F)F)F)C(F)(F)F

Technology Process of Bis[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]diazene

There total 6 articles about Bis[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]diazene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

4-trifluoromethyl-2,3,5,6-tetrafluoro-N,N-dichloroaniline (63995-48-2) → bis[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]diazene (65171-20-2)

Guidance literature:

at 160 ℃; under 760 Torr;

DOI:10.1039/c39800000997

Reference yield: 56.0%

4-trifluoromethyl-2,3,5,6-tetrafluoroaniline (651-83-2) → bis[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]diazene (65171-20-2)

Guidance literature:

With calcium hypochlorite; In neat (no solvent); for 0.5h; Reagent/catalyst; Milling;

DOI:10.1016/j.jfluchem.2018.10.012

Reference yield:

4-trifluoromethyl-2,3,5,6-tetrafluorophenylhydroxylamine (105637-41-0) → bis[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]diazene (65171-20-2) + 4-trifluoromethyl-2,3,5,6-tetrafluoroaniline (651-83-2) + 4,4'-bis-(trifluoromethyl)-octafluoroazoxybenzene (98583-25-6)

Guidance literature:

With phosphorus trichloride; In dichloromethane; at 20 ℃; for 20h;

DOI:10.1016/S0022-1139(00)82068-0

upstream raw materials:

4-trifluoromethyl-2,3,5,6-tetrafluoro-N,N-dichloroaniline

4-trifluoromethyl-2,3,5,6-tetrafluorophenylhydroxylamine

1,2,4,5-tetrafluoro-3-nitro-6-(trifluoromethyl)benzene

4-trifluoromethyl-2,3,5,6-tetrafluoroaniline

Downstream raw materials:

1-chloro-2,3,5,6-tetrafluoro-4-(trifluoromethyl)benzene