5-Amino-2-(2-(1-pyrrolidinyl)ethyl)-1H-benzo(de)isoquinoline-1,3(2H)-dione

Base Information

Chemical Name:5-Amino-2-(2-(1-pyrrolidinyl)ethyl)-1H-benzo(de)isoquinoline-1,3(2H)-dione
CAS No.:69408-83-9
Molecular Formula:C18H19N3O2
Molecular Weight:309.3624
Hs Code.:
NSC Number:308849
UNII:1TW4LP4IB1
DSSTox Substance ID:DTXSID50219564
Nikkaji Number:J952.297B
Wikidata:Q83096512
Pharos Ligand ID:2UR34PZ2VPD7
ChEMBL ID:CHEMBL1487460

Synonyms:69408-83-9;1TW4LP4IB1;NSC308849;MLS000757037;5-Amino-2-(2-(1-pyrrolidinyl)ethyl)-1H-benzo(de)isoquinoline-1,3(2H)-dione;UNII-1TW4LP4IB1;NSC 308849;5-amino-2-(2-pyrrolidin-1-ylethyl)benzo[de]isoquinoline-1,3-dione;NSC-308849;SMR000528909;1H-Benz[de]isoquinoline-1,3(2H)-dione, 5-amino-2-[2-(1-pyrrolidinyl)ethyl]-;1H-BENZ(DE)ISOQUINOLINE-1,3(2H)-DIONE, 5-AMINO-2-(2-(1-PYRROLIDINYL)ETHYL)-;5-Amino-2-(2-(1-pyrrolidinyl)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione;HMS2853D21;cid_328774;MADE-FA 2143;CHEMBL1487460;BDBM51259;DTXSID50219564;FA 2143;NCGC00246787-01;1H-Benz[de]isoquinoline-1, 5-amino-2-[2-(1-pyrrolidinyl)ethyl]-;5-amino-2-(2-pyrrolidinoethyl)benzo[de]isoquinoline-1,3-quinone;5-amino-2-[2-(1-pyrrolidinyl)ethyl]benzo[de]isoquinoline-1,3-dione;5-azanyl-2-(2-pyrrolidin-1-ylethyl)benzo[de]isoquinoline-1,3-dione;2-(2-Pyrrolizinoethyl)-5-amino-1H-benzo[de]isoquinoline-1,3(2H)-dione;{1H-Benz[de]isoquinoline-1,3(2H)-dione,} {5-amino-2-[2-(1-pyrrolidinyl)ethyl]-};5-AMINO-2-(2-(1-PYRROLIDINYL)ETHYL)-1H-BENZ(DE)ISOQUINOLINE-1,3(2H)-DIONE

Suppliers and Price of 5-Amino-2-(2-(1-pyrrolidinyl)ethyl)-1H-benzo(de)isoquinoline-1,3(2H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 5-Amino-2-(2-(1-pyrrolidinyl)ethyl)-1H-benzo(de)isoquinoline-1,3(2H)-dione

Chemical Property:

Vapor Pressure:3.34E-12mmHg at 25°C
Boiling Point:551.4°C at 760 mmHg
Flash Point:287.2°C
Density:1.331g/cm³
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:309.147726857
Heavy Atom Count:23
Complexity:489

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)CCN2C(=O)C3=CC=CC4=CC(=CC(=C43)C2=O)N

Technology Process of 5-Amino-2-(2-(1-pyrrolidinyl)ethyl)-1H-benzo(de)isoquinoline-1,3(2H)-dione

There total 4 articles about 5-Amino-2-(2-(1-pyrrolidinyl)ethyl)-1H-benzo(de)isoquinoline-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 7154-73-6
1-(2-aminoethyl)pyrrolidine

: 23204-38-8
3-amino-naphthalene-1,8-dicarboxylic acid-anhydride

: 69408-83-9
N-[1-pyrrolidinoethyl]-3-amino-1,8-naphthalimide

Guidance literature:: In ethanol; for 2h; Ambient temperature;

Reference yield:

: 3027-38-1
3-nitro-1,8-naphthalic anhydride

: 69408-83-9
N-[1-pyrrolidinoethyl]-3-amino-1,8-naphthalimide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / 10 percent Pd/C / dimethylformamide / 2280 Torr

2: 79 percent / ethanol / 2 h / Ambient temperature

With hydrogen; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;

Reference yield:

: 81-84-5
1,8-Naphthalic anhydride

: 69408-83-9
N-[1-pyrrolidinoethyl]-3-amino-1,8-naphthalimide

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid; nitric acid

2: tin(ll) chloride; hydrogenchloride

3: ethanol / 3 h / Reflux

With hydrogenchloride; sulfuric acid; nitric acid; tin(ll) chloride; In ethanol;
DOI:10.1016/j.bmc.2015.04.079