2-Hydroxy-1-naphthaldehyde p-methoxybenzoyl hydrazone

Base Information

• Chemical Name: 2-Hydroxy-1-naphthaldehyde p-methoxybenzoyl hydrazone
• CAS No.: 40111-51-1
• Molecular Formula: C19H16N2O3
• Molecular Weight: 320.348
• Mol file: 40111-51-1.mol

Synonyms:

Chemical Property of 2-Hydroxy-1-naphthaldehyde p-methoxybenzoyl hydrazone

Chemical Property:

• Melting Point: 236-238 °C(Solv: ethanol (64-17-5))
• PKA: 7.85±0.50(Predicted)
• PSA: 70.92000
• Density: 1.22±0.1 g/cm3(Predicted)
• LogP: 3.70880

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Hydroxy-1-naphthaldehyde p-methoxybenzoyl hydrazone

There total 2 articles about 2-Hydroxy-1-naphthaldehyde p-methoxybenzoyl hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

4-methoxybenzoic acid hydrazide (3290-99-1) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5) → 4-Methoxy-benzoic acid [1-(2-hydroxy-naphthalen-1-yl)-meth-(Z)-ylidene]-hydrazide (40111-51-1)

Guidance literature:

In ethanol; for 4h; Inert atmosphere; Reflux;

DOI:10.1016/j.jorganchem.2012.08.002

Reference yield:

4-methoxybenzoic acid hydrazide (3290-99-1) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5) → 4-Methoxy-benzoic acid [1-(2-hydroxy-naphthalen-1-yl)-meth-(E)-ylidene]-hydrazide (40111-51-1)

Guidance literature:

With acetic acid; In ethanol; Heating;

DOI:10.1021/je00054a044

Reference yield: 75.0%

C55H46As3ClORu + 4-Methoxy-benzoic acid [1-(2-hydroxy-naphthalen-1-yl)-meth-(Z)-ylidene]-hydrazide (40111-51-1) → C56H44As2N2O4Ru

Guidance literature:

With triethylamine; In benzene; for 6h; Inert atmosphere; Reflux;

DOI:10.1016/j.jorganchem.2012.08.002

upstream raw materials:

4-methoxybenzoic acid hydrazide

2-hydroxynaphthalene-1-carbaldehyde

Refernces

• 1、 Kanchanadevi, Appukutti,Ramesh, Rengan,Bhuvanesh, Nattamai. "Synthesis and molecular structure of ruthenium(III) benzoylhydrazone complexes: Substituents effect on transfer hydrogenation of ketones". . p. 49 - 57. Retrieved 2015/05/20.
• 2、 Edward, John T.,Gauthier, Mario,Chubb, Francis L.,Ponka, Premysl. "Synthesis of New Acylhydrazones as Iron-Chelating Compounds". . p. 538 - 540. Retrieved 2007/10/02.