Metamelfalan

Base Information

Chemical Name:Metamelfalan
CAS No.:1088-80-8
Molecular Formula:C₁₃H₁₈Cl₂N₂O₂
Molecular Weight:305.204
Hs Code.:2922499990
UNII:3B30XBE7S2
DSSTox Substance ID:DTXSID50883183
Nikkaji Number:J7.252D
Wikidata:Q27256990
NCI Thesaurus Code:C83946
ChEMBL ID:CHEMBL2107075
Mol file:1088-80-8.mol

Synonyms:m-L-sarcolysin;metamelfalan

Suppliers and Price of Metamelfalan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Metamelfalan
10mg
$ 1320.00

American Custom Chemicals Corporation
METAMELFALAN 95.00%
5MG
$ 505.73

Total 12 raw suppliers

Chemical Property of Metamelfalan

Chemical Property:

Vapor Pressure:5.2E-10mmHg at 25°C
Refractive Index:1.6070 (estimate)
Boiling Point:479.7°Cat760mmHg
Flash Point:243.9°C
PSA：66.56000
Density:1.32g/cm³
LogP:2.62530
XLogP3:-0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:304.0745332
Heavy Atom Count:19
Complexity:273

Purity/Quality:

99% ^*data from raw suppliers

Metamelfalan ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)N(CCCl)CCCl)CC(C(=O)O)N
Isomeric SMILES:C1=CC(=CC(=C1)N(CCCl)CCCl)C[C@@H](C(=O)O)N
Uses Metamelfalan is an impurity of Melphalan (M216900). Melphalan (M216900) is an antineoplastic.

Technology Process of Metamelfalan

There total 4 articles about Metamelfalan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 621-44-3
3-nitro-L-tyrosine

: 1088-80-8
L-m-sarcolysin

Guidance literature:: Multi-step reaction with 4 steps

3: MsCl, LiCl

With methanesulfonyl chloride; lithium chloride;
DOI:10.1016/0040-4039(95)02261-9

Reference yield:

: 173558-68-4
L-N-acetyl-3-aminophenyl-alanine methyl ester

: 1088-80-8
L-m-sarcolysin

Guidance literature:: Multi-step reaction with 3 steps

2: MsCl, LiCl

With methanesulfonyl chloride; lithium chloride;
DOI:10.1016/0040-4039(95)02261-9

Reference yield:

: 174019-19-3
L-N-acetyl-(m-bis-hydroxyethylamino)-phenylalanine methyl ester

: 1088-80-8
L-m-sarcolysin

Guidance literature:: Multi-step reaction with 2 steps

1: MsCl, LiCl

With methanesulfonyl chloride; lithium chloride;
DOI:10.1016/0040-4039(95)02261-9