5-Azatricyclo[8.2.2.24,7]hexadeca-4,6,10,12,13,15-hexaene

Base Information

Chemical Name:5-Azatricyclo[8.2.2.24,7]hexadeca-4,6,10,12,13,15-hexaene
CAS No.:37877-95-5
Molecular Formula:C15H15N
Molecular Weight:209.29
Hs Code.:
Mol file:37877-95-5.mol

Synonyms:[2](1,4)benzeno[2](2,5)pyridinophane;<2>paracyclo<2>(2,5)pyridinophane;5-Azatricyclo[8.2.2.24,7]hexadeca-4,6,10,12,13,15-hexaene;<2>Paracyclo<2>(2,5)pyridinophan;5-azatricyclo[8.2.2.24,7]hexadeca-1(12),4,6,10,13,15-hexaene;

Suppliers and Price of 5-Azatricyclo[8.2.2.24,7]hexadeca-4,6,10,12,13,15-hexaene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5-Azatricyclo[8.2.2.24,7]hexadeca-4,6,10,12,13,15-hexaene

Chemical Property:

Vapor Pressure:0.000317mmHg at 25°C
Boiling Point:330.6°C at 760 mmHg
PKA:5.74±0.20(Predicted)
Flash Point:141.2°C
PSA：12.89000
Density:1.074g/cm³
LogP:2.96540

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Azatricyclo[8.2.2.24,7]hexadeca-4,6,10,12,13,15-hexaene

There total 8 articles about 5-Azatricyclo[8.2.2.24,7]hexadeca-4,6,10,12,13,15-hexaene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 42239-19-0
2,11-dithia<3>(1,4)benzeno<3>(2,5)pyridinophane

: 37877-95-5
[2](1,4)benzeno[2](2,5)pyridinophane

Guidance literature:: With phosphorous acid trimethyl ester; for 18h; Ambient temperature; Irradiation;
DOI:10.1055/s-1999-3443

Reference yield:

: 100-26-5
Pyridine-2,5-dicarboxylic acid

: 37877-95-5
[2](1,4)benzeno[2](2,5)pyridinophane

Guidance literature:: Multi-step reaction with 6 steps

1: SOCl₂ / 8 h / Heating

2: 2 h / Heating

3: 67 percent / NaBH₄, CaCl₂ / ethanol / 16 h / Ambient temperature

4: HBr / acetic acid / 144 h / Ambient temperature

5: 62 percent / t-BuOK, Cs₂CO₃ / aq. ethanol / 16 h / Heating

6: 84 percent / P(OMe)3 / 18 h / Ambient temperature; Irradiation

With sodium tetrahydroborate; thionyl chloride; potassium tert-butylate; hydrogen bromide; caesium carbonate; calcium chloride; phosphorous acid trimethyl ester; In ethanol; acetic acid;
DOI:10.1055/s-1999-3443

Reference yield:

: 21514-99-8
2,5-bis[hydroxymethyl]-pyridine

: 37877-95-5
[2](1,4)benzeno[2](2,5)pyridinophane

Guidance literature:: Multi-step reaction with 3 steps

1: HBr / acetic acid / 144 h / Ambient temperature

2: 62 percent / t-BuOK, Cs₂CO₃ / aq. ethanol / 16 h / Heating

3: 84 percent / P(OMe)3 / 18 h / Ambient temperature; Irradiation

With potassium tert-butylate; hydrogen bromide; caesium carbonate; phosphorous acid trimethyl ester; In ethanol; acetic acid;
DOI:10.1055/s-1999-3443