roxifiban

Base Information

• Chemical Name: roxifiban
• CAS No.: 176022-59-6
• Molecular Formula: C23H33N5O8
• Molecular Weight: 507.53682
• Mol file: 176022-59-6.mol

Synonyms:roxifiban

Chemical Property of roxifiban

Chemical Property:

• Vapor Pressure: 1.45E-24mmHg at 25°C
• Boiling Point: 764.3°Cat760mmHg
• Flash Point: 416.1°C
• PSA: 209.47000
• Density: g/cm³
• LogP: 2.40910

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of roxifiban

There total 2 articles about roxifiban which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

→ (R)-methyl 3-[[[3-[4-(aminoiminomethyl)phenyl]-4,5-dihydro-5-isoxazolyl]acetyl]amino]-N-(butoxycarbonyl)-L-alanine monoacetate (176022-59-6)

Guidance literature:

Reference yield:

ammonium acetate (631-61-8,92206-38-7) + (S)-2-Butoxycarbonylamino-3-{2-[(R)-3-(4-methoxycarbonimidoyl-phenyl)-4,5-dihydro-isoxazol-5-yl]-acetylamino}-propionic acid methyl ester → (R)-methyl 3-[[[3-[4-(aminoiminomethyl)phenyl]-4,5-dihydro-5-isoxazolyl]acetyl]amino]-N-(butoxycarbonyl)-L-alanine monoacetate (176022-59-6)

Guidance literature:

Yield given;

DOI:10.1016/0040-4039(96)00694-6

upstream raw materials:

ammonium acetate

Refernces

• 1、 Zhang, Lin-Hua,Anzalone,Ma,Kauffman,Storace,Ward. "The chiral specific synthesis of DMP 754, a platelet GP IIb/IIIa antagonist". . p. 4455 - 4458. Retrieved 1996.