2,5-Bis(3-methoxyphenyl)-1,3,4-oxadiazole

Base Information

Chemical Name:2,5-Bis(3-methoxyphenyl)-1,3,4-oxadiazole
CAS No.:19748-58-4
Molecular Formula:C16H14 N2 O3
Molecular Weight:282.299
Hs Code.:
European Community (EC) Number:243-268-6
NSC Number:90473
DSSTox Substance ID:DTXSID70173432
Nikkaji Number:J225.264C
Wikidata:Q83043495
Mol file:19748-58-4.mol

Synonyms:2,5-Bis(3-methoxyphenyl)-1,3,4-oxadiazole;19748-58-4;2,5-di-(3-Methoxyphenyl)-1,3,4-oxadiazole;EINECS 243-268-6;1,3,4-Oxadiazole, 2,5-bis(3-methoxyphenyl)-;NSC90473;2,5-bis-(3-Methoxyphenyl)-1,3,4-oxadiazole;SCHEMBL1181062;DTXSID70173432;NSC 90473;NSC-90473;AKOS024371074;2,5-di(m-methoxyphenyl)-1,3,4-oxadiazole;FT-0610254;2,5-Bis(3-methoxyphenyl)-1,3,4-oxadiazole #

Suppliers and Price of 2,5-Bis(3-methoxyphenyl)-1,3,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,5-BIS(3-METHOXYPHENYL)-1,3,4-OXADIAZOLE 95.00%
5MG
$ 503.99

Total 9 raw suppliers

Chemical Property of 2,5-Bis(3-methoxyphenyl)-1,3,4-oxadiazole

Chemical Property:

Vapor Pressure:2.87E-08mmHg at 25°C
Boiling Point:461.8°Cat760mmHg
Flash Point:233.1°C
PSA：57.38000
Density:1.189g/cm³
LogP:3.42080
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:282.10044231
Heavy Atom Count:21
Complexity:299

Purity/Quality:

99% ^*data from raw suppliers

2,5-BIS(3-METHOXYPHENYL)-1,3,4-OXADIAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.;

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C2=NN=C(O2)C3=CC(=CC=C3)OC

Technology Process of 2,5-Bis(3-methoxyphenyl)-1,3,4-oxadiazole

There total 4 articles about 2,5-Bis(3-methoxyphenyl)-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 586-38-9
3-Methoxybenzoic acid

: 19748-58-4
2,5-bis(3-methoxyphenyl)-1,3,4-oxadiazole

Guidance literature:: With hydrazine dihydrochloride; phosphoric acid; phosphorus pentoxide; at 130 ℃; for 0.0833333h; microwave irradiation;
DOI:10.1081/SCC-100103330

Reference yield:

: 7732-39-0
3-methoxy-N'-(3-methoxybenzoyl)benzohydrazide

: 19748-58-4
2,5-bis(3-methoxyphenyl)-1,3,4-oxadiazole

Guidance literature:: With Burgess Reagent; In tetrahydrofuran; at 100 ℃; for 0.166667h; Microwave;

Reference yield:

: 1711-05-3
m-anisoyl chloride

: 19748-58-4
2,5-bis(3-methoxyphenyl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; hydrazine hydrate / N,N-dimethyl-formamide / 0.5 h / Cooling with ice

2: Burgess Reagent / tetrahydrofuran / 0.17 h / 100 °C / Microwave

With Burgess Reagent; hydrazine hydrate; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran;