3-((2-Benzofuranylmethyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one

Base Information

Chemical Name:3-((2-Benzofuranylmethyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one
CAS No.:135525-72-3
Molecular Formula:C17H18N2O2
Molecular Weight:282.337
Hs Code.:
DSSTox Substance ID:DTXSID50159451
Nikkaji Number:J425.110E
Wikidata:Q83027785
ChEMBL ID:CHEMBL316785
Mol file:135525-72-3.mol

Synonyms:135525-72-3;CHEMBL316785;3-((2-Benzofuranylmethyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one;3-((Benzofuran-2-ylmethyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one;3-[(2-Benzofuranylmethyl)amino]-5-ethyl-6-methylpyridin-2(1H)-one;Pyridinone deriv. 8;BDBM1284;DTXSID50159451;3-(benzofuran-2-ylmethylamino)-5-ethyl-6-methyl-1H-pyridin-2-one;5-Ethyl-6-methyl-3-[[(benzofuran-2-yl)methyl]amino]pyridin-2(1H)-one;3-[(1-benzofuran-2-ylmethyl)amino]-5-ethyl-6-methyl-1,2-dihydropyridin-2-one

Suppliers and Price of 3-((2-Benzofuranylmethyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-((2-Benzofuranylmethyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one

Chemical Property:

Vapor Pressure:9.52E-11mmHg at 25°C
Boiling Point:515.8°C at 760 mmHg
Flash Point:265.7°C
Density:1.2g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:282.136827821
Heavy Atom Count:21
Complexity:481

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C(NC(=O)C(=C1)NCC2=CC3=CC=CC=C3O2)C

Technology Process of 3-((2-Benzofuranylmethyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one

There total 4 articles about 3-((2-Benzofuranylmethyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 139393-81-0
5-ethyl-6-methyl-3-nitro-2(1H)-pyridinone

: 135525-72-3
3-[(Benzofuran-2-ylmethyl)-amino]-5-ethyl-6-methyl-1H-pyridin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / H₂ / Pd/C / methanol; tetrahydrofuran

2: p-TsOH / methanol / Ambient temperature

3: NaBH₄ / ethanol / 1 h / Ambient temperature

With sodium tetrahydroborate; hydrogen; toluene-4-sulfonic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol;
DOI:10.1021/jm00099a007

Reference yield:

: 143745-99-7
2-ethyl-3-oxobutanal sodium salt

: 135525-72-3
3-[(Benzofuran-2-ylmethyl)-amino]-5-ethyl-6-methyl-1H-pyridin-2-one

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / aq. piperidinium acetate

2: 68 percent / H₂ / Pd/C / methanol; tetrahydrofuran

3: p-TsOH / methanol / Ambient temperature

4: NaBH₄ / ethanol / 1 h / Ambient temperature

With sodium tetrahydroborate; hydrogen; piperdinium acetate; toluene-4-sulfonic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol;
DOI:10.1021/jm00099a007