1'-benzylspiro[isoquinoline-1(2H),4'-piperidine]-3(4H)-one hydrochloride

Base Information

Chemical Name:1'-benzylspiro[isoquinoline-1(2H),4'-piperidine]-3(4H)-one hydrochloride
CAS No.:15198-52-4
Molecular Formula:C₂₀H₂₂N₂O*ClH
Molecular Weight:342.868
Hs Code.:
Mol file:15198-52-4.mol

Synonyms:Spiro[isoquinoline-1(2H),4'-piperidin]-3(4H)-one,1'-(phenylmethyl)-, monohydrochloride (9CI);Spiro[isoquinoline-1(2H),4'-piperidin]-3(4H)-one, 1'-benzyl-, monohydrochloride(8CI)

Suppliers and Price of 1'-benzylspiro[isoquinoline-1(2H),4'-piperidine]-3(4H)-one hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 1'-benzylspiro[isoquinoline-1(2H),4'-piperidine]-3(4H)-one hydrochloride

Chemical Property:

Boiling Point:537.1°Cat760mmHg
Flash Point:278.6°C
PSA：32.34000
Density:g/cm³
LogP:3.91890

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1'-benzylspiro[isoquinoline-1(2H),4'-piperidine]-3(4H)-one hydrochloride

There total 1 articles about 1'-benzylspiro[isoquinoline-1(2H),4'-piperidine]-3(4H)-one hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 103-81-1
Benzeneacetamide

: 15198-52-4
1'-benzyl-2H-spiro[isoquinoline-1,4'-piperidine]-3(4H)-one hydrochloride

Guidance literature:: With hydrogenchloride; phosphorus pentoxide; phosphoric acid; In diethylene glycol dimethyl ether; at 100 ℃; for 64h;

Reference yield: 86.0%

: 15198-52-4
1'-benzyl-2H-spiro[isoquinoline-1,4'-piperidine]-3(4H)-one hydrochloride

: spiro[isoquinoline-1(2H),4'-piperidine]-3(4H)-one hydrochloride

Guidance literature:: With hydrogen; palladium dihydroxide; In ethanol; water; for 3h; under 760 Torr; Ambient temperature;
DOI:10.1248/cpb.46.242