9H-Indeno[2,1-c]pyridin-9-one

Base Information

• Chemical Name: 9H-Indeno[2,1-c]pyridin-9-one
• CAS No.: 5061-91-6
• Molecular Formula: C12H7NO
• Molecular Weight: 181.194
• Hs Code.: 2933990090
• Mol file: 5061-91-6.mol

Synonyms:

Chemical Property of 9H-Indeno[2,1-c]pyridin-9-one

Chemical Property:

• PSA: 57.34000
• LogP: 4.76080

Purity/Quality:

95% ^*data from raw suppliers

Indeno[2,1-c]pyridin-9-one 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9H-Indeno[2,1-c]pyridin-9-one

There total 33 articles about 9H-Indeno[2,1-c]pyridin-9-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-phenylpyridine-3-carboxylic acid methyl ester (70647-05-1) → 9H-indeno(2,1-c)pyridin-9-one (5061-91-6)

Guidance literature:

With PPA; Polyphosphoric acid (PPA); at 210 ℃; for 4h;

DOI:10.3987/COM-92-6199

Reference yield: 85.0%

4-phenylpyridine-3-carbonitrile (39065-51-5) → 9H-indeno(2,1-c)pyridin-9-one (5061-91-6)

Guidance literature:

With PPA; Polyphosphoric acid (PPA); at 210 ℃; for 10h;

DOI:10.3987/COM-92-6199

Reference yield: 67.0%

2-(pyridin-4-yl)benzoic acid (133362-99-9) → 9H-indeno(2,1-c)pyridin-9-one (5061-91-6)

Guidance literature:

With 2,2,6,6-tetramethylpiperidinyl-lithium; In tetrahydrofuran; at 20 ℃; for 18h;

DOI:10.1016/S0040-4020(03)00761-0

upstream raw materials:

mesityl-(4-phenyl-[3]pyridyl)-ketone

(4-phenyl-[3]pyridyl)-(2,3,5,6-tetramethyl-phenyl)-ketone

4-phenylpyridine-3-carbonitrile

4-phenylpyridine-3-carboxylic acid methyl ester

Downstream raw materials:

2-aza-9-hydroxy-9-fluorenylcarbonyl-L-prolyl-2-(tert-butyloxycarbonylaminomethyl)-5-chlorobenzylamide

Refernces

• 1、 Wu, Peng,Zhu, Jun,Zhang, Zhen,Dou, Dehai,Wang, Hedan,Wei, Bin,Wang, Zixing. "Nitrogen introduction of spirobifluorene to form α-, β-, γ-, and δ-aza-9,9′-spirobifluorenes: New bipolar system for efficient blue organic light-emitting diodes". . p. 185 - 191. Retrieved 2018/04/17.
• 2、 -. "Aza-spirobifluorene derivative and preparation method thereof". Paragraph 0087-0090; 0093. . Retrieved 2017/08/18.