4-(2-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine

Base Information

Chemical Name:4-(2-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine
CAS No.:75663-55-7
Molecular Formula:C₁₂H₁₄FN
Molecular Weight:191.248
Hs Code.:

Synonyms:

Suppliers and Price of 4-(2-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-(2-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine

Chemical Property:

Vapor Pressure:0.00687mmHg at 25°C
Boiling Point:270.4°Cat760mmHg
Flash Point:117.3°C
Density:1.079g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-(2-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine

There total 18 articles about 4-(2-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 72365-19-6
4-(2-fluorophenyl)-4-hydroxy-1-methylpiperidine

: 75663-55-7
4-(2-fluorophenyl)-1,2,3,6-tetrahydro-1-methylpyridine

: 72365-21-0
4-(benzylthio)-4-(2-fluorophenyl)-1-methylpiperidine

Guidance literature:: With boron trifluoride; acetic acid; phenylmethanethiol; at 60 ℃; for 15h;
DOI:10.1021/jm00133a016

Reference yield:

: 1072-85-1
o-fluorobromobenzene

: 75663-55-7
4-(2-fluorophenyl)-1,2,3,6-tetrahydro-1-methylpyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) THF, -70 deg C, 1 h, 2.) THF, from -60 deg C to RT

2: BF₃, glacial AcOH / 15 h / 60 °C

With n-butyllithium; boron trifluoride; acetic acid;
DOI:10.1021/jm00133a016

Reference yield:

: 1445-73-4
1-Methyl-4-piperidone

: 75663-55-7
4-(2-fluorophenyl)-1,2,3,6-tetrahydro-1-methylpyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) THF, -70 deg C, 1 h, 2.) THF, from -60 deg C to RT

2: BF₃, glacial AcOH / 15 h / 60 °C

With n-butyllithium; boron trifluoride; acetic acid;
DOI:10.1021/jm00133a016