4-Ethoxyphenoxyacetic acid

Base Information

• Chemical Name: 4-Ethoxyphenoxyacetic acid
• CAS No.: 5327-91-3
• Molecular Formula: C10H12 O4
• Molecular Weight: 196.203
• Hs Code.: 2918990090
• European Community (EC) Number: 226-212-5
• NSC Number: 4161
• UNII: MYD776SC2N
• DSSTox Substance ID: DTXSID40201397
• Nikkaji Number: J151.005C
• Wikidata: Q83074615
• Mol file: 5327-91-3.mol

Synonyms:5327-91-3;2-(4-ethoxyphenoxy)acetic acid;(4-ethoxy-phenoxy)-acetic acid;4-Ethoxyphenoxyacetic acid;(4-ethoxyphenoxy)acetic acid;MYD776SC2N;Acetic acid, (p-ethoxyphenoxy)- (6CI);NSC-4161;EINECS 226-212-5;MFCD03419318;NSC4161;Acetic acid, 2-(4-ethoxyphenoxy)-;Enamine_005102;UNII-MYD776SC2N;2-(4-ethoxyphenoxy)aceticacid;SCHEMBL4651646;Acetic acid,(p-ethoxyphenoxy)-;DTXSID40201397;Acetic acid, (4-ethoxyphenoxy)-;HMS1408H20;NSC 4161;STK291370;AKOS000104204;IDI1_007689;ACETIC ACID, (P-ETHOXYPHENOXY)-;BS-38111;EN300-05237;Z56896865;F1967-6759

Chemical Property of 4-Ethoxyphenoxyacetic acid

Chemical Property:

• Vapor Pressure: 3.59E-05mmHg at 25°C
• Boiling Point: 339.4°C at 760 mmHg
• Flash Point: 133.9°C
• PSA: 55.76000
• LogP: 1.54870
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 196.07355886
• Heavy Atom Count: 14
• Complexity: 173

Purity/Quality:

99% ^*data from raw suppliers

2-(4-ethoxyphenoxy)aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=CC=C(C=C1)OCC(=O)O

Technology Process of 4-Ethoxyphenoxyacetic acid

There total 2 articles about 4-Ethoxyphenoxyacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

→ (4-ethoxyphenoxy)acetic acid (5327-91-3)

Guidance literature:

With sodium hydroxide; In water; Reflux;

Reference yield:

4-Ethoxyphenol (622-62-8) + chloroacetic acid (79-11-8) → (4-ethoxyphenoxy)acetic acid (5327-91-3)

Guidance literature:

With sodium hydroxide;

Reference yield: 24.0%

(4-ethoxyphenoxy)acetic acid (5327-91-3) + 1-(3,4-Dichlorobenzyl)-4-piperidinylamine (92539-28-1) → C22H26Cl2N2O3

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃;

upstream raw materials:

4-Ethoxyphenol

chloroacetic acid

Downstream raw materials:

(4-ethoxy-phenoxy)-acetyl chloride

N-Dimethylcarbamoylmethyl-2-(4-ethoxy-phenoxy)-acetamide

2-(4-Ethoxy-phenoxy)-N-methylcarbamoylmethyl-acetamide

ethyl 2-(4-ethoxyphenoxy)acetate