2-(2-chloro-4-methylsulfonyl-benzoyl)cyclohexane-1,3-dione

Base Information

• Chemical Name: 2-(2-chloro-4-methylsulfonyl-benzoyl)cyclohexane-1,3-dione
• CAS No.: 114680-61-4
• Molecular Formula: C₁₄H₁₃ClO₅S
• Molecular Weight: 328.773
• Mol file: 114680-61-4.mol

Synonyms:ICI-A 0051;Mikado; SC 0051; Sulcotrione

Chemical Property of 2-(2-chloro-4-methylsulfonyl-benzoyl)cyclohexane-1,3-dione

Chemical Property:

• Boiling Point: 574.5°Cat760mmHg
• Flash Point: 301.2°C
• PSA: 93.73000
• Density: 1.428g/cm³
• LogP: 2.94530

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-chloro-4-methylsulfonyl-benzoyl)cyclohexane-1,3-dione

There total 4 articles about 2-(2-chloro-4-methylsulfonyl-benzoyl)cyclohexane-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(2-chloro-4-methanesulfonylbenzoyloxy)cyclohex-2-enone (114911-83-0) + 2-hydroxy-2-methylpropanenitrile (75-86-5) → sulcotrione (99105-77-8,114680-61-4,123174-48-1)

Guidance literature:

With triethylamine; In acetonitrile;

Reference yield:

1,3-cylohexanedione (504-02-9) + 2-chloro-4-(methylsulphonyl)benzoyl chloride (106904-10-3) → sulcotrione (99105-77-8,114680-61-4,123174-48-1)

Guidance literature:

1,3-cylohexanedione; 2-chloro-4-(methylsulphonyl)benzoyl chloride; With triethylamine; In toluene;

With sodium hydroxide; In water; toluene; at 45 ℃; for 0.5h;

With pyridine; hydrogenchloride; In water; at 12 ℃; pH=2.7;

Reference yield:

2-chloro-4-(methanesulfonyl)benzoic acid (53250-83-2) + 1,3-cylohexanedione (504-02-9) + potassium carbonate (584-08-7) + 2-hydroxy-2-methylpropanenitrile (75-86-5) → sulcotrione (99105-77-8,114680-61-4,123174-48-1)

Guidance literature:

With hydrogenchloride; thionyl chloride; triethylamine; In 1,4-dioxane; N-methyl-acetamide; ethyl acetate; acetonitrile;

upstream raw materials:

1,3-cylohexanedione

2-chloro-4-(methylsulphonyl)benzoyl chloride

2-chloro-4-(methanesulfonyl)benzoic acid

potassium carbonate

Refernces

• 1、 -. "NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND". . . Retrieved 2017/08/26.
• 2、 -. "METHOD FOR PRODUCING SPECIFIC CRYSTALLINE MODIFICATIONS OF POLYMORPHOUS SUBSTANCES". Page 13. . Retrieved 2008/06/13.