3-(2-Aminoethyl)-5-methoxybenzofuran, hydrochloride

Base Information

Chemical Name:3-(2-Aminoethyl)-5-methoxybenzofuran, hydrochloride
CAS No.:22137-01-5
Molecular Formula:C₁₁H₁₃NO₂*ClH
Molecular Weight:227.691
Hs Code.:
Mol file:22137-01-5.mol

Synonyms:3-(2-Aminoethyl)-5-methoxybenzofuran, hydrochloride;BENZOFURAN, 3-(2-AMINOETHYL)-5-METHOXY-, HYDROCHLORIDE;22137-01-5;LS-34885;3-Benzofuranethanamine, 5-methoxy-, hydrochloride

Suppliers and Price of 3-(2-Aminoethyl)-5-methoxybenzofuran, hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-(2-Aminoethyl)-5-methoxybenzofuran, hydrochloride

Chemical Property:

Vapor Pressure:0.000565mmHg at 25°C
Boiling Point:311.4°C at 760 mmHg
Flash Point:142.1°C
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:227.0713064
Heavy Atom Count:15
Complexity:186

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)OC=C2CC[NH3+].[Cl-]

Technology Process of 3-(2-Aminoethyl)-5-methoxybenzofuran, hydrochloride

There total 2 articles about 3-(2-Aminoethyl)-5-methoxybenzofuran, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 39581-44-7
2-(5-methoxybenzo[b]furan-3-yl)acetonitrile

: 22137-01-5
2-(5-methoxybenzofuran-3-yl)ethylamine hydrochloride

Guidance literature:: 2-(5-methoxybenzo[b]furan-3-yl)acetonitrile; With ammonia; hydrogen; nickel; In ethanol; at 60 ℃; for 3h; under 45003.6 Torr;

With hydrogenchloride; In diethyl ether;

Reference yield:

: 39581-55-0
5-methoxy-benzofuran-3-one

: 22137-01-5
2-(5-methoxybenzofuran-3-yl)ethylamine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: 80 percent / NaH / tetrahydrofuran / 2 h / 20 °C

2.1: NH₃; H₂ / Raney Nickel / ethanol / 3 h / 60 °C / 45003.6 Torr

2.2: 67 percent / hydrochloric acid gas / diethyl ether

With ammonia; hydrogen; sodium hydride; nickel; In tetrahydrofuran; ethanol;