4-Carbamoyloxy-1-(3-(4-fluorophenoxy)propyl)-trans-decahydroquinoline (axial form)

Base Information

Chemical Name:4-Carbamoyloxy-1-(3-(4-fluorophenoxy)propyl)-trans-decahydroquinoline (axial form)
CAS No.:78778-28-6
Molecular Formula:C₁₉H₂₇FN₂O₃
Molecular Weight:350.433
Hs Code.:
DSSTox Substance ID:DTXSID201000015

Synonyms:4-Carbamoyloxy-1-(3-(4-fluorophenoxy)propyl)-trans-decahydroquinoline (axial form);4-Quinolinol, decahydro-1-(3-(4-fluorophenoxy)propyl)-, carbamate (ester), (4-alpha,4a-beta,8a-alpha)-;78778-28-6;DTXSID201000015;LS-142520;{2-[3-(4-Fluorophenoxy)propyl]-4-hydroxyoctahydroquinolin-1(2H)-yl}carbamic acid

Suppliers and Price of 4-Carbamoyloxy-1-(3-(4-fluorophenoxy)propyl)-trans-decahydroquinoline (axial form)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-Carbamoyloxy-1-(3-(4-fluorophenoxy)propyl)-trans-decahydroquinoline (axial form)

Chemical Property:

Density:1.28g/cm³
XLogP3:1.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:366.19548551
Heavy Atom Count:26
Complexity:459

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2C(C1)C(CC(N2NC(=O)O)CCCOC3=CC=C(C=C3)F)O
Isomeric SMILES:C1CC[C@@H]2[C@@H](C1)[C@H](CC(N2NC(=O)O)CCCOC3=CC=C(C=C3)F)O

Technology Process of 4-Carbamoyloxy-1-(3-(4-fluorophenoxy)propyl)-trans-decahydroquinoline (axial form)

There total 6 articles about 4-Carbamoyloxy-1-(3-(4-fluorophenoxy)propyl)-trans-decahydroquinoline (axial form) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: chlorocarbonyloxy-4β <(fluoro-4' phenoxy)-3 propyl>-1 trans decahydroquinoleine

: 78778-19-5,78778-28-6
carbaminoyloxy-4β <(fluoro-4' phenoxy)-3 propyl>-1 trans-decahydroquinoleine

Guidance literature:: With ammonia; In toluene; at 20 - 22 ℃; for 48h; Yield given;

Reference yield:

: C₁₉H₂₅ClFNO₃

: 78778-19-5,78778-28-6
Carbamic acid (4S,4aS,8aS)-1-[3-(4-fluoro-phenoxy)-propyl]-decahydro-quinolin-4-yl ester

Guidance literature:: With ammonia; In toluene; at 20 - 22 ℃; for 48h;

Reference yield:

: 1716-42-3
1-(3-chloropropoxy)-4-fluorobenzene

: 78778-19-5,78778-28-6
carbaminoyloxy-4β <(fluoro-4' phenoxy)-3 propyl>-1 trans-decahydroquinoleine

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent / Na₂CO₃ / butan-1-ol / 72 h / Heating

2: toluene / 48 h / 20 - 22 °C

3: NH₃ / toluene / 48 h / 20 - 22 °C

With ammonia; sodium carbonate; In toluene; butan-1-ol;