1-(4-Hydroxyquinolin-3-yl)ethanone

Base Information

Chemical Name:1-(4-Hydroxyquinolin-3-yl)ethanone
CAS No.:6622-19-1
Molecular Formula:C11H9NO2
Molecular Weight:187.198
Hs Code.:
NSC Number:56541
DSSTox Substance ID:DTXSID50984705
Nikkaji Number:J1.017.252G
Wikidata:Q82972001

Synonyms:3-acetyl-1H-quinolin-4-one;1-(4-hydroxyquinolin-3-yl)ethanone;3-ACETYLQUINOLIN-4(1H)-ONE;6622-19-1;74037-78-8;1-(4-Hydroxyquinolin-3-yl)ethan-1-one;67503-70-2;NSC56541;4-hydroxy-3-acetylquinoline;3-acetyl-4(1H)-quinolinone;SCHEMBL2931679;SCHEMBL8116061;DTXSID50984705;NZXUIQMHGFPOHI-UHFFFAOYSA-N;NSC-56541;STL513585;1,4-Dihydro-3-acetyl-4-oxoquinoline;AKOS030494118;A835372

Suppliers and Price of 1-(4-Hydroxyquinolin-3-yl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 30 raw suppliers

Chemical Property of 1-(4-Hydroxyquinolin-3-yl)ethanone

Chemical Property:

Vapor Pressure:6.13E-05mmHg at 25°C
Boiling Point:345.5°C at 760 mmHg
Flash Point:153.8°C
Density:1.236g/cm³
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:187.063328530
Heavy Atom Count:14
Complexity:306

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CNC2=CC=CC=C2C1=O

Technology Process of 1-(4-Hydroxyquinolin-3-yl)ethanone

There total 1 articles about 1-(4-Hydroxyquinolin-3-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6622-18-0
2-acetyl-3-(phenylamino)acrylic acid ethyl ester

: 108-24-7
acetic anhydride

: 6622-19-1
3-acetyl-4-hydroxyquinoline

Guidance literature:: With sulfuric acid;

Reference yield:

: 6622-19-1
3-acetyl-4-hydroxyquinoline

: 98348-51-7
3-hydroxy-2-phenyl-pyrano[3,2-c]quinolin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: aq. NaOH / methanol / Heating

2: aq. HCl, pentyl nitrite / ethanol / Ambient temperature

3: H₂SO₄ / H₂O / Heating

With hydrogenchloride; sodium hydroxide; n-Amyl nitrite; sulfuric acid; In methanol; ethanol; water;
DOI:10.1039/jr9610002796

Reference yield:

: 6622-19-1
3-acetyl-4-hydroxyquinoline

: 98596-21-5
2-phenyl-pyrano[3,2-c]quinolin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: aq. NaOH / methanol / Heating

2: Br₂ / CHCl₃

3: Py

With pyridine; sodium hydroxide; bromine; In methanol; chloroform;
DOI:10.1039/jr9610002796