4-(4-Amino-2-iodophenyl)-3-iodoaniline

Base Information

• Chemical Name: 4-(4-Amino-2-iodophenyl)-3-iodoaniline
• CAS No.: 54391-31-0
• Molecular Formula: C12H10I2N2
• Molecular Weight: 436.034
• Hs Code.: 2921590090
• NSC Number: 170080
• DSSTox Substance ID: DTXSID70305271
• Nikkaji Number: J89.861I
• Wikidata: Q82051848
• Mol file: 54391-31-0.mol

Synonyms:54391-31-0;2,2'-diiodo-4,4'-diaminobiphenyl;4-(4-amino-2-iodophenyl)-3-iodoaniline;2,2'-diiodobenzidine;NSC170080;SCHEMBL5851353;DTXSID70305271;PGJJPWRSBHDEOP-UHFFFAOYSA-N;NSC-170080;2,2'-Diiodo-[1,1'-biphenyl]-4,4'-diamine

Chemical Property of 4-(4-Amino-2-iodophenyl)-3-iodoaniline

Chemical Property:

• Boiling Point: 490.6oC at 760 mmHg
• Flash Point: 250.5oC
• PSA: 52.04000
• Density: 2.143g/cm3
• LogP: 4.88960
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 435.89334
• Heavy Atom Count: 16
• Complexity: 213

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1N)I)C2=C(C=C(C=C2)N)I

Technology Process of 4-(4-Amino-2-iodophenyl)-3-iodoaniline

There total 10 articles about 4-(4-Amino-2-iodophenyl)-3-iodoaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2,2'-Diiodo-4,4'-dinitrobiphenyl (61761-98-6) → 2,2'-diiodo-4,4'-diaminobiphenyl (54391-31-0)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; In ethanol; water; for 1h;

Reference yield: 42.0%

bis-(3-iodo-phenyl)-diazene-N-oxide (19618-17-8) → 2,2'-diiodo-4,4'-diaminobiphenyl (54391-31-0)

Guidance literature:

With acetic acid; zinc; In tetrahydrofuran; at 40 - 55 ℃;

Reference yield:

m-iodonitrobenzene (645-00-1) → 2,2'-diiodo-4,4'-diaminobiphenyl (54391-31-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydroxide / ethanol; ethylene glycol / 3 h / 70 °C

2.1: zinc; phosphoric acid; acetic acid / tetrahydrofuran / 0.5 h / 40 - 55 °C

2.2: 1 h / 0 °C

With phosphoric acid; acetic acid; sodium hydroxide; zinc; In tetrahydrofuran; ethanol; ethylene glycol;

DOI:10.1002/pola.27461

upstream raw materials:

2,2'-Diiodo-4,4'-dinitrobiphenyl

bis-(3-iodo-phenyl)-diazene-N-oxide

2,2′-diiodo-4,4′-biphenyldicarboxylic acid

(+/-)-2,2'-Diiod-biphenyl-4,4'-dicarbonsaeurechlorid

Refernces

• 1、 Perkins, Wade,Fischer, Felix R.. "Inserting Porphyrin Quantum Dots in Bottom-Up Synthesized Graphene Nanoribbons". . p. 17687 - 17691. Retrieved 2017.
• 2、 Tapaswi, Pradip Kumar,Choi, Myeon-Cheon,Nagappan, Saravanan,Ha, Chang-Sik. "Synthesis and characterization of highly transparent and hydrophobic fluorinated polyimides derived from perfluorodecylthio substituted diamine monomers". . p. 479 - 488. Retrieved 2015/03/03.