3-Phenyl-2-azetidinone

Base Information

Chemical Name:3-Phenyl-2-azetidinone
CAS No.:17197-57-8
Molecular Formula:C9H9 N O
Molecular Weight:147.177
Hs Code.:2933790090
NSC Number:173143
Nikkaji Number:J54.690I
Mol file:17197-57-8.mol

Synonyms:3-phenylazetidin-2-one;3-Phenyl-2-azetidinone;17197-57-8;3-Fenil-2-azetidinone;2-AZETIDINONE, 3-PHENYL-;L 1759;3-Fenil-2-azetidinone [Italian];NSC 173143;BRN 0120633;5-21-08-00053 (Beilstein Handbook Reference);SCHEMBL14515493;NSC173143;STL300227;AKOS006274423;NSC-173143;LS-23161;L-1759

Suppliers and Price of 3-Phenyl-2-azetidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-Phenyl-2-azetidinone

Chemical Property:

Vapor Pressure:3.5E-05mmHg at 25°C
Boiling Point:353.8°C at 760 mmHg
Flash Point:205.5°C
PSA：29.10000
Density:1.152g/cm³
LogP:1.22880
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:147.068413911
Heavy Atom Count:11
Complexity:161

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(=O)N1)C2=CC=CC=C2

Technology Process of 3-Phenyl-2-azetidinone

There total 7 articles about 3-Phenyl-2-azetidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: cis-4-(formyloxy)-3-phenyl-2-azetidinone

: 17197-57-8
3-phenyl-azetidin-2-one

Guidance literature:: With sodium tetrahydroborate; In isopropyl alcohol; at 0 ℃;
DOI:10.1016/0040-4039(95)00492-U

Reference yield: 72.0%

: 184423-97-0
N-(4-methoxyphenyl)-3-phenylazetidin-2-one

: 17197-57-8
3-phenyl-azetidin-2-one

Guidance literature:: With ammonium cerium(IV) nitrate; In water; acetonitrile;
DOI:10.1021/jo9612685

Reference yield:

: 133505-02-9
cis-1-(p-methoxyphenyl)-4-formyl-3-phenyl-2-azetidinone

: 17197-57-8
3-phenyl-azetidin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / m-CPBA / CH₂Cl₂ / 18 h / Ambient temperature

2: 75 percent / CAN / acetonitrile; H₂O / 0 °C

3: 80 percent / NaBH₄ / H₂O; propan-2-ol / 0 °C

With sodium tetrahydroborate; ammonium cerium(IV) nitrate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; water; isopropyl alcohol; acetonitrile;
DOI:10.1021/jo9612685