hexadecyl glucoside

Base Information

• Chemical Name: hexadecyl glucoside
• CAS No.: 75319-63-0
• Molecular Formula: C22H44 O6
• Molecular Weight: 404.58
• Hs Code.: 2940000080
• Mol file: 75319-63-0.mol

Synonyms:Glucopyranoside,hexadecyl (6CI); Hexadecyl glucoside; Hexadecyl monoglucoside; Hexadecyl b-D-glucopyranoside

Chemical Property of hexadecyl glucoside

Chemical Property:

• Vapor Pressure: 4.38E-14mmHg at 25°C
• Boiling Point: 543.6°C at 760 mmHg
• Flash Point: 282.6°C
• PSA: 99.38000
• Density: 1.07g/cm³
• LogP: 3.28420

Purity/Quality:

99% ^*data from raw suppliers

Hexadecyl b-D-glucopyranoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of hexadecyl glucoside

There total 25 articles about hexadecyl glucoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

hexadecyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside (85339-28-2,94591-53-4,123814-47-1) → hexadecyl β-D-galactopyranoside (103000-88-0,75319-63-0,123000-26-0,142696-64-8,146453-38-5,96790-89-5)

Guidance literature:

With ammonium hydroxide; In methanol; for 3h; Reflux;

DOI:10.1016/j.bmcl.2012.01.069

Reference yield: 97.0%

hexadecyl-2,3,4,6-tetra-O-acetate-β-D-glucopyranoside (85339-28-2) → hexadecyl β-D-glucopyranoside (75319-63-0,96790-89-5)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃;

DOI:10.1039/b805015e

Reference yield:

1-Hexadecanol (36653-82-4,124-29-8) → hexadecyl β-D-glucopyranoside (75319-63-0,96790-89-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: TMS-triflate; molecular sieves / CH₂Cl₂ / 0.5 h / 20 °C

1.2: CH₂Cl₂ / 20 °C

2.1: NH₃ / methanol

With molecular sieve; trimethylsilyl trifluoromethanesulfonate; ammonia; In methanol; dichloromethane;

DOI:10.1016/S0009-3084(01)00196-7

upstream raw materials:

hexadecyl-2,3,4,6-tetra-O-acetate-β-D-glucopyranoside

1-Hexadecanol

β-D-glucose pentaacetate

D-glucose pentaacetate

Downstream raw materials:

1-O-palmityl-D-glucuronic acid

Refernces

• 1、 Bogdanová, Kate?ina,Combet, Sophie,D?ubák, Petr,Gurská, Soňa,Hajdúch, Marian,Kanjaková, Nina,Klunda, Tomá?,Kolá?, Milan,Poláková, Monika,Uhríková, Daniela. "Antimicrobial and cytotoxic activity of (thio)alkyl hexopyranosides, nonionic glycolipid mimetics". . . Retrieved 2020/01/30.
• 2、 Kurochkina,Budanova,Sebyakin, Yu. L.. "Design and synthesis of cluster neoglycoconjugates based on D-glucose". . p. 1496 - 1503. Retrieved 2015/02/18.