7-N-(4-O-Sialosylphenyl)-9-methoxymitosane methyl ester

Base Information

Chemical Name:7-N-(4-O-Sialosylphenyl)-9-methoxymitosane methyl ester
CAS No.:134136-44-0
Molecular Formula:C33H41 N5 O14
Molecular Weight:731.7
Hs Code.:
DSSTox Substance ID:DTXSID00928472
Mol file:134136-44-0.mol

Synonyms:7-N-(4-O-sialosylphenyl)-9-methoxymitosane methyl ester;7-SPMM

Suppliers and Price of 7-N-(4-O-Sialosylphenyl)-9-methoxymitosane methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 7-N-(4-O-Sialosylphenyl)-9-methoxymitosane methyl ester

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:1058.9°Cat760mmHg
Flash Point:594.2°C
PSA：292.16000
Density:1.58g/cm³
LogP:-1.18730
XLogP3:-1.4
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:17
Rotatable Bond Count:14
Exact Mass:731.26500100
Heavy Atom Count:52
Complexity:1560

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)NC5=CC=C(C=C5)OC6(CC(C(C(O6)C(C(CO)O)O)NC(=O)C)O)C(=O)OC

Technology Process of 7-N-(4-O-Sialosylphenyl)-9-methoxymitosane methyl ester

There total 3 articles about 7-N-(4-O-Sialosylphenyl)-9-methoxymitosane methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 134136-43-9
7-N-<4-O-(Methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-didedoxy-α-D-glycero-D-galacto-2-nonulopyranosylonate)phenyl>-9a-methoxymitosane

: 134136-44-0
7-N-<4-O-(Methyl 5-acetamido-3,5-didedoxy-α-D-glycero-D-galacto-2-nonulopyranosylonate)phenyl>-9a-methoxymitosane

Guidance literature:: With methanol; sodium methylate; In methanol; for 0.416667h; Ambient temperature;
DOI:10.1248/cpb.39.255

Reference yield:

: 59694-37-0
methyl (4-nitrophenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-oxy-α-D-glycero-D-galacto-2-nonulopyranosid)onate

: 134136-44-0
7-N-<4-O-(Methyl 5-acetamido-3,5-didedoxy-α-D-glycero-D-galacto-2-nonulopyranosylonate)phenyl>-9a-methoxymitosane

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / hydrogen / PtO₂ / ethyl acetate / 2 h / Ambient temperature

2: 51 percent / methanol / 120 h / Ambient temperature

3: 75 percent / 28 percent sodium methoxide-methanol / methanol / 0.42 h / Ambient temperature

With methanol; hydrogen; sodium methylate; platinum(IV) oxide; In methanol; ethyl acetate;
DOI:10.1248/cpb.39.255

Reference yield:

: 130087-26-2
methyl (4-aminophenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-oxy-α-D-glycero-D-galacto-2-nonulopyranosid)onate

: 134136-44-0
7-N-<4-O-(Methyl 5-acetamido-3,5-didedoxy-α-D-glycero-D-galacto-2-nonulopyranosylonate)phenyl>-9a-methoxymitosane

Guidance literature:: Multi-step reaction with 2 steps

1: 51 percent / methanol / 120 h / Ambient temperature

2: 75 percent / 28 percent sodium methoxide-methanol / methanol / 0.42 h / Ambient temperature

With methanol; sodium methylate; In methanol;
DOI:10.1248/cpb.39.255