1-Methylphospholan-3-one 1-oxide

Base Information

• Chemical Name: 1-Methylphospholan-3-one 1-oxide
• CAS No.: 21229-61-8
• Molecular Formula: C₅H₉O₂P
• Molecular Weight: 132.099
• NSC Number: 129545
• DSSTox Substance ID: DTXSID90299345
• Mol file: 21229-61-8.mol

Synonyms:21229-61-8;1-methylphospholan-3-one 1-oxide;NSC129545;DTXSID90299345;NSC-129545;1-Methyl-1-oxo-1I>>5-phospholan-3-one

Chemical Property of 1-Methylphospholan-3-one 1-oxide

Chemical Property:

• Vapor Pressure: 3.19E-05mmHg at 25°C
• Boiling Point: 355.1°C at 760 mmHg
• Flash Point: 168.6°C
• Density: 1.14g/cm³
• XLogP3: -1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 132.03401652
• Heavy Atom Count: 8
• Complexity: 162

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CP1(=O)CCC(=O)C1

Technology Process of 1-Methylphospholan-3-one 1-oxide

There total 2 articles about 1-Methylphospholan-3-one 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxy-1-methyl-2,3-dihydro-1H-phosphole 1-oxide (21229-62-9) → 1-Methyl-3-phospholanon-1-oxid (21229-61-8)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/jo00919a023

Reference yield:

→ 1-Methyl-3-phospholanon-1-oxid (21229-61-8)

Guidance literature:

/BRN= 606833/ (III),HCl (stark verduennt);

DOI:10.1039/c19680001463

Reference yield:

1-Methyl-3-phospholanon-1-oxid (21229-61-8) → Methyl-(3-oxobutyl)-phosphinsaeure (49849-26-5)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/jo00919a023

upstream raw materials:

4-methoxy-1-methyl-2,3-dihydro-1H-phosphole 1-oxide

Downstream raw materials:

Methyl-(3-oxobutyl)-phosphinsaeure