S-[2-(N7-guanyl)ethyl]GSH

Base Information

• Chemical Name: S-[2-(N7-guanyl)ethyl]GSH
• CAS No.: 100840-34-4
• Molecular Formula: C₁₇H₂₄N₈O₇S
• Molecular Weight: 484.493
• Mol file: 100840-34-4.mol

Synonyms:Glycine,N-[S-[2-(2-amino-1,6-dihydro-6-oxo-7H-purin-7-yl)ethyl]-N-L-g-glutamyl-L-cysteinyl]-;S-[2-(N7-Guanyl)ethyl]glutathione; S-[2-(N7-guanyl)ethyl]GSH

Chemical Property of S-[2-(N7-guanyl)ethyl]GSH

Chemical Property:

• PSA: 281.68000
• Density: 1.77g/cm³
• LogP: 0.03600
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: S-[2-(N7-Guanyl)ethyl]glutathione is a known DNA adduct formed as a result of glutathione (GSH)-dependent base-substitution mutations caused by the carcinogen ethylene dibromide (EDB).

Technology Process of S-[2-(N7-guanyl)ethyl]GSH

There total 2 articles about S-[2-(N7-guanyl)ethyl]GSH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

G (118-00-3) → S-<2-(N7-guanyl)ethyl>glutathione (100840-34-4)

Guidance literature:

Multi-step reaction with 2 steps

1: AgNO₃

With silver nitrate;

DOI:10.1021/ja00218a045

Reference yield:

glutathion (70-18-8) + N7-(2-bromoethyl)guanosine → S-<2-(N7-guanyl)ethyl>glutathione (100840-34-4)

Guidance literature:

DOI:10.1021/ja00218a045

upstream raw materials:

glutathion

G