2-Amino-N-(pyridin-2-YL)ethanesulfonamide

Base Information

• Chemical Name: 2-Amino-N-(pyridin-2-YL)ethanesulfonamide
• CAS No.: 31644-48-1
• Molecular Formula: C7H11 N3 O2 S
• Molecular Weight: 201.249
• Hs Code.: 2935009090
• DSSTox Substance ID: DTXSID70185530
• Wikidata: Q72441659
• Mol file: 31644-48-1.mol

Synonyms:2-(aminoethanesulfonylamino)pyridine;tauraminopyridine

Chemical Property of 2-Amino-N-(pyridin-2-YL)ethanesulfonamide

Chemical Property:

• Vapor Pressure: 5.65E-06mmHg at 25°C
• Melting Point: 140-141 °C
• Boiling Point: 379.9°Cat760mmHg
• PKA: 8.52±0.10(Predicted)
• Flash Point: 183.6°C
• PSA: 93.46000
• Density: 1.404g/cm³
• LogP: 1.63610
• Storage Temp.: 2-8°C
• XLogP3: -0.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 201.05719778
• Heavy Atom Count: 13
• Complexity: 235

Purity/Quality:

99%min ^*data from raw suppliers

2-Amino-N-(pyridin-2-yl)ethanesulfonamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=NC(=C1)NS(=O)(=O)CCN

Technology Process of 2-Amino-N-(pyridin-2-YL)ethanesulfonamide

There total 5 articles about 2-Amino-N-(pyridin-2-YL)ethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.46%

2-aminopyridine (504-29-0) + 2–((tert-butoxycarbonyl)amino)ethyl-1-sulfonic acid → taurine-[2]pyridylamide (31644-48-1)

Guidance literature:

2-aminopyridine; 2–((tert-butoxycarbonyl)amino)ethyl-1-sulfonic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 24h;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.5h;

Reference yield:

2-aminopyridine (504-29-0) → taurine-[2]pyridylamide (31644-48-1)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: ethanol; aqueous N₂H₄+H₂O

With pyridine; ethanol; hydrazine hydrate;

DOI:10.1021/ja01198a047

Reference yield:

2-phthalimido-ethanesulfonic acid-[2]pyridylamide (83708-21-8) → taurine-[2]pyridylamide (31644-48-1)

Guidance literature:

With ethanol; hydrazine hydrate;

DOI:10.1021/ja01198a047

upstream raw materials:

2-benzoylamino-ethanesulfonic acid-[2]pyridylamide

2-phthalimido-ethanesulfonic acid-[2]pyridylamide

2-aminopyridine

Refernces