(+)-Myristinin A

Base Information

Chemical Name:(+)-Myristinin A
CAS No.:145904-69-4
Molecular Formula:C33H40 O7
Molecular Weight:548.67
Hs Code.:
Mol file:145904-69-4.mol

Synonyms:1-Dodecanone,1-[3-[3,4-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxyphenyl]-,trans-(+)-; (+)-Myristinin A; Myristinin A; YM 26567-1

Suppliers and Price of (+)-Myristinin A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(+)-MYRISTININ A 95.00%
5MG
$ 504.93

Total 2 raw suppliers

Chemical Property of (+)-Myristinin A

Chemical Property:

Purity/Quality:: (+)-MYRISTININ A 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+)-Myristinin A

There total 50 articles about (+)-Myristinin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 850816-11-4
(2R,3R,4R)-2-(4-benzyloxyphenyl)-7-benzyloxy-4-(2,4,6-tribenzyloxy-3-(dodecanoyl)phenyl)chroman

: 137130-31-5,145904-69-4
(2R,3R,4R)-2-(4-hydroxyphenyl)-7-hydroxy-4-(2,4,6-trihydroxy-3-(dodecanoyl)phenyl)chromane

Guidance literature:: With palladium dihydroxide; In tetrahydrofuran; methanol; for 0.5h;
DOI:10.1021/ja042727j

Reference yield:

: 850816-16-9
(2R,3S)-2-(4-benzyloxyphenyl)-7-benzyloxychroman-3-ol

: 137130-31-5,145904-69-4
(2R,3R,4R)-2-(4-hydroxyphenyl)-7-hydroxy-4-(2,4,6-trihydroxy-3-(dodecanoyl)phenyl)chromane

Guidance literature:: Multi-step reaction with 7 steps

1: 93 percent / 4-(dimethylamino)pyridine / CH₂Cl₂ / 2 h / 20 °C

2: 82 percent / DDQ; 4-(dimethylamino)pyridine / CH₂Cl₂ / 0 - 20 °C

3: 75 percent / TMSOTf / CH₂Cl₂ / 1 h / 0 °C

4: 92 percent / potassium carbonate / tetrahydrofuran; methanol / 48 h / 20 °C

5: 76 percent / 4-(dimethylamino)pyridine / acetonitrile / 24 h / 50 °C

6: 95 percent / SnBu₃H; AIBN / toluene / 6 h / 100 °C

7: BBr₃ / CH₂Cl₂ / -78 - 25 °C

With dmap; 2,2'-azobis(isobutyronitrile); trimethylsilyl trifluoromethanesulfonate; tri-n-butyl-tin hydride; boron tribromide; potassium carbonate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; methanol; dichloromethane; toluene; acetonitrile;
DOI:10.1021/ol060511b

Reference yield:

: (E)-1-(4-benzyloxyphenyl)-3-(4-benzyloxy-2-hydroxyphenyl)propene

: 137130-31-5,145904-69-4
(2R,3R,4R)-2-(4-hydroxyphenyl)-7-hydroxy-4-(2,4,6-trihydroxy-3-(dodecanoyl)phenyl)chromane

Guidance literature:: Multi-step reaction with 14 steps

1.1: 100 percent / imidazole / dimethylformamide / 20 °C

2.1: 84 percent / AD-Mix α; methanesulfonamide / 2-methyl-propan-2-ol; H2O / 20 °C

3.1: 92 percent / pyridinium p-toluenesulfonate / CH₂Cl₂ / 1 h / 20 °C

4.1: 100 percent / tert-n-butylammonium fluoride / tetrahydrofuran / 1 h / 20 °C

5.1: 89 percent / triethyl orthoformate; pyridinium p-toluenesulfonate / 1,2-dichloro-ethane / 2 h / 60 °C

6.1: 98 percent / K₂CO₃ / methanol; tetrahydrofuran / 2 h / 20 °C

7.1: 94 percent / Dess-Martin periodinane / CH₂Cl₂ / 2 h / 20 °C

8.1: 78 percent / LiBr; L-selectride / tetrahydrofuran / -78 - 20 °C

9.1: 93 percent / 4-N,N-dimethylaminopyridine / CH₂Cl₂ / 2 h / 20 °C

10.1: 79 percent / DDQ; 4-N,N-dimethylaminopyridine / CH₂Cl₂ / 0.25 h / 0 °C

11.1: 78 percent / TMSOTf / tetrahydrofuran / -35 - -5 °C / pH 7

12.1: 100 percent / K₂CO₃ / tetrahydrofuran; methanol / 20 °C

13.1: 4-N,N-dimethylaminopyridine; phenyl trichloroformate / acetonitrile / 6 h / 70 °C

13.2: 65 percent / SnBu₃H / AIBN / toluene / 8 h / 110 °C

14.1: 75 percent / Pd(OH)2/C / methanol; tetrahydrofuran / 0.5 h

With 1H-imidazole; dmap; palladium dihydroxide; AD-mix-α; methanesulfonamide; trimethylsilyl trifluoromethanesulfonate; phenyl trichloroformate; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; L-Selectride; potassium carbonate; Dess-Martin periodane; orthoformic acid triethyl ester; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium bromide; dmap; In tetrahydrofuran; methanol; dichloromethane; water; 1,2-dichloro-ethane; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol; 2.1: Sharpless asymmetric dihydroxylation;
DOI:10.1021/ja042727j