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Technology Process of Dexverapamil Hydrochloride

Dexverapamil Hydrochloride

Base Information
  • Chemical Name:Dexverapamil Hydrochloride
  • CAS No.:38176-02-2
  • Molecular Formula:C27H38 N2 O4 . Cl H
  • Molecular Weight:509.07784
  • Hs Code.:
  • European Community (EC) Number:253-810-3
  • NSC Number:632821
  • UNII:B0P742MK5O
  • DSSTox Substance ID:DTXSID80959103
  • Wikidata:Q27147334
  • NCI Thesaurus Code:C156452
  • ChEMBL ID:CHEMBL1994739
  • Mol file:38176-02-2.mol
Dexverapamil Hydrochloride

Synonyms:38176-02-2;Dexverapamil Hydrochloride;(R)-Verapamil Hydrochloride;(R)-(+)-Verapamil Hydrochloride;(R)-Verapamil (hydrochloride);Verapamil hydrochloride, (+)-;(2r)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile hydrochloride(1:1);(+)-verapamil hydrochloride;UNII-B0P742MK5O;(+)-[3-cyano-3-(3,4-dimethoxyphenyl)hex-6-yl](5,6-dimethoxyphenethyl)methylammonium chloride;B0P742MK5O;CHEBI:77739;EINECS 253-810-3;NSC-632821;(+)-(3-Cyano-3-(3,4-dimethoxyphenyl)hex-6-yl)(5,6-dimethoxyphenethyl)methylammonium chloride;dexverapamil HCl;dexverapamil.HCl;R(+)-VERAPAMIL HYDROCHLORIDE;SCHEMBL8759750;CHEMBL1994739;DTXSID80959103;(2R)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride;DEXVERAPAMIL MONOHYDROCHLORIDE;NSC632821;AKOS040736385;LU-33925;MS-29129;HY-135336;CS-0111666;R-Verapamil Hydrochloride from Knoll Pharma.;VERAPAMIL (R)-FORM HYDROCHLORIDE [MI];F82532;Q27147334;(2R)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile hydrochloride;(4R)-4-cyano-4-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N,5-dimethylhexan-1-aminium chloride;2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile--hydrogen chloride (1/1);BENZENEACETONITRILE, .ALPHA.-(3-((2-(3,4-DIMETHOXYPHENYL)ETHYL)METHYLAMINO)PROPYL)-3,4-DIMETHOXY-.ALPHA.-(1-METHYLETHYL)-, MONOHYDROCHLORIDE, (.ALPHA.R)-;BENZENEACETONITRILE, .ALPHA.-(3-((2-(3,4-DIMETHOXYPHENYL)ETHYL)METHYLAMINO)PROPYL)-3,4-DIMETHOXY-.ALPHA.-(1-METHYLETHYL)-, MONOHYDROCHLORIDE, (R)-

Suppliers and Price of Dexverapamil Hydrochloride
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • (R)-(+)-VerapamilHydrochloride
  • 2mg
  • $ 335.00
  • Sigma-Aldrich
  • R(+)-Verapamil monohydrochloride hydrate ≥98% (HPLC), powder
  • 5mg
  • $ 223.00
  • Sigma-Aldrich
  • R(+)-Verapamil monohydrochloride hydrate ≥98% (HPLC), powder
  • 25mg
  • $ 848.00
  • ChemScene
  • (R)-Verapamil(hydrochloride) 98.54%
  • 100mg
  • $ 1850.00
  • ChemScene
  • (R)-Verapamil(hydrochloride) 98.54%
  • 50mg
  • $ 1100.00
  • ChemScene
  • (R)-Verapamil(hydrochloride) 98.54%
  • 10mg
  • $ 360.00
  • ChemScene
  • (R)-Verapamil(hydrochloride) 98.54%
  • 5mg
  • $ 200.00
  • Biosynth Carbosynth
  • (2R)-2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-isopropylpentanenitrile hydrochloride
  • 1 mg
  • $ 318.00
  • Biosynth Carbosynth
  • (2R)-2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-isopropylpentanenitrile hydrochloride
  • 2 mg
  • $ 578.10
  • Biosynth Carbosynth
  • (2R)-2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-isopropylpentanenitrile hydrochloride
  • 5 mg
  • $ 1051.10
Total 12 raw suppliers
Chemical Property of Dexverapamil Hydrochloride
Chemical Property:
  • Melting Point:129-131?C 
  • PSA：65.15000 
  • LogP:0.43398 
  • Storage Temp.:Refrigerator 
  • Solubility.:H2O: >30mg/mL 
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:6
  • Rotatable Bond Count:13
  • Exact Mass:490.2598354
  • Heavy Atom Count:34
  • Complexity:606
Purity/Quality:

99% *data from raw suppliers

(R)-(+)-VerapamilHydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes:T 
  • Statements: 23/24/25 
  • Safety Statements: 22-36/37/39-45 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl
  • Isomeric SMILES:CC(C)[C@@](CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl
  • Recent EU Clinical Trials:A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Phase 2 Study to Evaluate the Safety and Efficacy of R-Verapamil in the Prophylaxis of Episodic Cluster Headache
  • Uses R(+)-Verapamil monohydrochloride hydrate has been used as a P-glycoprotein (gp) inhibitor, to detect P-gp expression on the SK-OV-3 and SK-OV-3/DDP cell surface by flow cytometry. It has also been used as a calcium channel blocker, to evaluate its effect on doxorubicin (DOX) cytotoxicity.
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