3,5-Dichlorosalicylic acid

Base Information

Chemical Name:3,5-Dichlorosalicylic acid
CAS No.:320-72-9
Deprecated CAS:50516-74-0
Molecular Formula:C7H4Cl2O3
Molecular Weight:207.013
Hs Code.:29182900
European Community (EC) Number:206-281-8
NSC Number:30109
UNII:O6PXR32G3V
DSSTox Substance ID:DTXSID3044914
Nikkaji Number:J54.309H
Wikidata:Q27285414
Pharos Ligand ID:SBDMRUXT3MHG
Metabolomics Workbench ID:71500
ChEMBL ID:CHEMBL449129
Mol file:320-72-9.mol

Synonyms:3,5-dichlorosalicylic acid;beta-CDP-3

Suppliers and Price of 3,5-Dichlorosalicylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
3,5-Dichlorosalicylic Acid >98.0%(GC)(T)
500g
$ 381.00

TCI Chemical
3,5-Dichlorosalicylic Acid >98.0%(GC)(T)
25g
$ 42.00

SynQuest Laboratories
3,5-Dichloro-2-hydroxybenzoic acid 99.0%
25 g
$ 21.00

SynQuest Laboratories
3,5-Dichloro-2-hydroxybenzoic acid 99.0%
5 g
$ 16.00

SynQuest Laboratories
3,5-Dichloro-2-hydroxybenzoic acid 99.0%
100 g
$ 55.00

Sigma-Aldrich
3,5-Dichlorosalicylic acid 97%
25g
$ 50.90

Crysdot
3,5-Dichloro-2-hydroxybenzoicacid 98%
1000g
$ 261.00

Chemenu
3,5-Dichloro-2-hydroxybenzoicacid 95+%
1000g
$ 243.00

Chemenu
3,5-Dichloro-2-hydroxybenzoicacid 95+%
500g
$ 163.00

Biosynth Carbosynth
3,5-Dichlorosalicylic acid
2 kg
$ 500.00

Total 79 raw suppliers

Chemical Property of 3,5-Dichlorosalicylic acid

Chemical Property:

Appearance/Colour:white crystalline powder
Vapor Pressure:0.000142mmHg at 25°C
Melting Point:221-224 °C
Refractive Index:1.4845 (estimate)
Boiling Point:319.292 °C at 760 mmHg
PKA:1.99±0.14(Predicted)
Flash Point:146.903 °C
PSA：57.53000
Density:1.665 g/cm³
LogP:2.39720
Storage Temp.:Inert atmosphere,Room Temperature
Solubility.:Solubility in methanol (almost transparency).
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:205.9537494
Heavy Atom Count:12
Complexity:186

Purity/Quality:

97% ^*data from raw suppliers

3,5-Dichlorosalicylic Acid >98.0%(GC)(T) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi
Statements: 36/37/38-22
Safety Statements: 37/39-26-36

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Other Classes -> Benzoic Acid Derivatives
Canonical SMILES:C1=C(C=C(C(=C1C(=O)O)O)Cl)Cl
Uses 3,5-Dichlorosalicylic acid is a bio-active drug and is a potential inhibitor of human 20α-hydroxysteroid dehydrogenase. It also finds its application as medicine and dyes intermediates.

Technology Process of 3,5-Dichlorosalicylic acid

There total 45 articles about 3,5-Dichlorosalicylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 69-72-7,25496-36-0,8052-31-1
salicylic acid

: 320-72-9
3,5-dichlorosalicylic acid

Guidance literature:: With chlorine; In acetic acid; at 35 ℃;
DOI:10.1023/B:RUGC.0000039088.87053.eb

Reference yield:

: 7606-87-3
methyl 3,5-dichlorosalicylate

: 320-72-9
3,5-dichlorosalicylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: butanone; aqueous potassium carbonate; potassium iodide

2: aqueous methanol. KOH-solution

3: 230 °C

With potassium hydroxide; potassium carbonate; butanone; potassium iodide;
DOI:10.1021/ja01251a038