8-Methyl-5,6-dihydro-4H-pyrazino-[3,2,1-jk]carbazole hydrochloride

Base Information

• Chemical Name: 8-Methyl-5,6-dihydro-4H-pyrazino-[3,2,1-jk]carbazole hydrochloride
• CAS No.: 15932-34-0
• Molecular Formula: C15H14 N2 . Cl H
• Molecular Weight: 258.75
• Hs Code.: 2933990090
• Mol file: 15932-34-0.mol

Synonyms:4H-Pyrazino[3,2,1-jk]carbazole,5,6-dihydro-8-methyl-, monohydrochloride (8CI,9CI)

Chemical Property of 8-Methyl-5,6-dihydro-4H-pyrazino-[3,2,1-jk]carbazole hydrochloride

Chemical Property:

• Vapor Pressure: 5.91E-06mmHg at 25°C
• Melting Point: 200-203 °C
• Boiling Point: 379.3°C at 760 mmHg
• Flash Point: 183.2°C
• PSA: 17.30000
• LogP: 4.08660

Purity/Quality:

98%min ^*data from raw suppliers

8-Methyl-5,6-dihydro-4H-pyrazino-[3,2,1-jk]carbazole hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-Methyl-5,6-dihydro-4H-pyrazino-[3,2,1-jk]carbazole hydrochloride

There total 1 articles about 8-Methyl-5,6-dihydro-4H-pyrazino-[3,2,1-jk]carbazole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one (3449-48-7,812649-03-9) + α-bromoacetaldehyde dibutylacetal (40398-10-5) → 5,6-dihydro-8-methyl-4H-pyrazino<3,2,1-j,k>carbazole hydrochloride (15932-34-0)

Guidance literature:

With hydrogenchloride; ammonium acetate; In acetic acid; at 120 ℃; for 10h;

DOI:10.1007/BF00505759

Reference yield: 76.0%

5,6-dihydro-8-methyl-4H-pyrazino<3,2,1-j,k>carbazole hydrochloride (15932-34-0) → 2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole monohydrochloride (16154-78-2,145511-50-8,145511-51-9)

Guidance literature:

With sodium tetrahydroborate; 1.)15 deg C, 30 min 2.)80 deg C, 30 min;

DOI:10.1007/BF00505759

upstream raw materials:

6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one

α-bromoacetaldehyde dibutylacetal

Downstream raw materials:

2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole monohydrochloride

Refernces