methyl (4R)-4-[(3S,5R,10S,13R,14R,17R)-3-acetyloxy-4,4,10,13,14-pentamethyl-7,11-dioxo-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate

Base Information

Chemical Name:methyl (4R)-4-[(3S,5R,10S,13R,14R,17R)-3-acetyloxy-4,4,10,13,14-pentamethyl-7,11-dioxo-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
CAS No.:57706-74-8
Molecular Formula:C₃₀H₄₄O₆
Molecular Weight:500.676
Hs Code.:
NSC Number:34201

methyl (4R)-4-[(3S,5R,10S,13R,14R,17R)-3-acetyloxy-4,4,10,13,14-pentamethyl-7,11-dioxo-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate

Synonyms:NSC34201;57706-74-8;NSC-34201

Suppliers and Price of methyl (4R)-4-[(3S,5R,10S,13R,14R,17R)-3-acetyloxy-4,4,10,13,14-pentamethyl-7,11-dioxo-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of methyl (4R)-4-[(3S,5R,10S,13R,14R,17R)-3-acetyloxy-4,4,10,13,14-pentamethyl-7,11-dioxo-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate

Chemical Property:

Vapor Pressure:1.03E-12mmHg at 25°C
Boiling Point:563.3°Cat760mmHg
Flash Point:235.1°C
PSA：86.74000
Density:1.13g/cm³
LogP:5.61470
XLogP3:5.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:500.31378912
Heavy Atom Count:36
Complexity:1020

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCC(=O)OC)C1CCC2(C1(CC(=O)C3=C2C(=O)CC4C3(CCC(C4(C)C)OC(=O)C)C)C)C
Isomeric SMILES:C[C@H](CCC(=O)OC)[C@H]1CC[C@@]2([C@@]1(CC(=O)C3=C2C(=O)C[C@@H]4[C@@]3(CC[C@@H](C4(C)C)OC(=O)C)C)C)C

Technology Process of methyl (4R)-4-[(3S,5R,10S,13R,14R,17R)-3-acetyloxy-4,4,10,13,14-pentamethyl-7,11-dioxo-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate

There total 8 articles about methyl (4R)-4-[(3S,5R,10S,13R,14R,17R)-3-acetyloxy-4,4,10,13,14-pentamethyl-7,11-dioxo-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 30655-16-4
(R)-methyl-4-((3S,5R,10S,13R,14R,17R)-3-acetoxy-4,4,10,13,14-pentamethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate

: 57706-74-8
(R)-methyl-4-((3S,5R,10S,13R,14R,17R)-3-acetoxy-4,4,10,13,14-pentamethyl-7,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate

Guidance literature:: With potassium permanganate; 18-crown-6 ether; In dichloromethane; water; at 20 ℃; for 24h;
DOI:10.1021/jo400275p

Reference yield: 40.0%

: 35844-33-8
Methyl-3β-acetoxy-25,26,27-trinorlanosta-7,9(11)-dien-24-oat

: 57706-74-8
(R)-methyl-4-((3S,5R,10S,13R,14R,17R)-3-acetoxy-4,4,10,13,14-pentamethyl-7,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate

: 76987-94-5
(R)-4-((3S,5R,10S,13R,14S,17R)-3-Acetoxy-4,4,10,13,14-pentamethyl-7-oxo-2,3,4,5,6,7,8,10,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-pentanoic acid methyl ester

Guidance literature:: With chromium(VI) oxide; In chloroform; acetic acid; at 50 ℃; for 6h;
DOI:10.1007/BF00903668

Reference yield:

: 76987-91-2
C₃₀H₄₈O₅

: 57706-74-8
(R)-methyl-4-((3S,5R,10S,13R,14R,17R)-3-acetoxy-4,4,10,13,14-pentamethyl-7,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate

Guidance literature:: Multi-step reaction with 2 steps

1: BF₃*Et₂O / Ambient temperature

2: 39 percent / CrO₃ / acetic acid; CHCl₃ / 6 h / 50 °C

With chromium(VI) oxide; boron trifluoride diethyl etherate; In chloroform; acetic acid;
DOI:10.1007/BF00903668