2-Hydroxyethyl 6,8-dideoxy-7-O-methyl-6-[[[(2S)-1-methyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside

Base Information

• Chemical Name: 2-Hydroxyethyl 6,8-dideoxy-7-O-methyl-6-[[[(2S)-1-methyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside
• CAS No.: 19246-70-9
• Molecular Formula: C17H32N2O7S
• Molecular Weight: 408.51
• Mol file: 19246-70-9.mol

Synonyms:U-6340;2-hydroxyethyl 6,8-dideoxy-7-o-methyl-6-[(1-methylprolyl)amino]-1-thiooctopyranoside;Desalitcetin;

Chemical Property of 2-Hydroxyethyl 6,8-dideoxy-7-O-methyl-6-[[[(2S)-1-methyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside

Chemical Property:

• Vapor Pressure: 6.48E-21mmHg at 25°C
• Boiling Point: 671.6°C at 760 mmHg
• Flash Point: 360°C
• PSA: 160.51000
• Density: 1.35g/cm³
• LogP: -1.08840

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Hydroxyethyl 6,8-dideoxy-7-O-methyl-6-[[[(2S)-1-methyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside

There total 5 articles about 2-Hydroxyethyl 6,8-dideoxy-7-O-methyl-6-[[[(2S)-1-methyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H31N3O8S + S-adenosyl-L-methionine (485-80-3,15519-60-5,60018-85-1,60018-86-2,79845-28-6) → C16H30N2O7S + desalicetin (19246-70-9)

Guidance literature:

With pyridoxal 5'-phosphate; CcbF enzyme; O-methyltransferase Ccb₄; oxidoreductase Ccb₅; NADPH; In aq. phosphate buffer; at 30 ℃; for 2h; pH=7.5; Enzymatic reaction;

DOI:10.1021/jacs.6b01751

Reference yield:

→ desalicetin (19246-70-9)

Guidance literature:

With sodium hydroxide;

Reference yield:

→ desalicetin (19246-70-9)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

S-adenosyl-L-methionine