Triiodothyronine sulfate

Base Information

Chemical Name:Triiodothyronine sulfate
CAS No.:31135-55-4
Molecular Formula:C₁₅H₁₂I₃NO₇S
Molecular Weight:731.042
Hs Code.:
DSSTox Substance ID:DTXSID80185066
Wikidata:Q27116476
Metabolomics Workbench ID:38238
ChEMBL ID:CHEMBL2074889
Mol file:31135-55-4.mol

Synonyms:triiodothyronine sulfate;triiodothyronine sulfuric ester

Suppliers and Price of Triiodothyronine sulfate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,3’,5-Triiodo-L-thyronine4’-O-Sulfate
2.5mg
$ 185.00

Medical Isotopes, Inc.
3,3?,5-Triiodo-L-thyronine4?-O-sulfate
10 mg
$ 1190.00

Chemtos
Liothyroninesulfate
0
$ 9990.00

American Custom Chemicals Corporation
LIOTHYRONINE SULFATE 95.00%
10MG
$ 4589.55

Total 7 raw suppliers

Chemical Property of Triiodothyronine sulfate

Chemical Property:

Boiling Point:°Cat760mmHg
PKA:-4.33±0.18(Predicted)
Flash Point:°C
PSA：144.53000
Density:2.434g/cm³
LogP:5.20980
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
XLogP3:1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:7
Exact Mass:730.7469
Heavy Atom Count:27
Complexity:605

Purity/Quality:

98% ^*data from raw suppliers

3,3’,5-Triiodo-L-thyronine4’-O-Sulfate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)O)N)I)I)OS(=O)(=O)O
Isomeric SMILES:C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)O)N)I)I)OS(=O)(=O)O
Uses 3,3’5-Triiodo-L-thyronine 4’O-Sulfate is the sulfoconjugated metabolite of 3,3’5-Triiodo-L-thyronine (T795380). 3,3’,5-Triiodo-L-thyronine 4’-O-Sulfate is the sulfoconjugated metabolite of 3,3’,5-Triiodo-L-thyronine (T795380).

Technology Process of Triiodothyronine sulfate

There total 3 articles about Triiodothyronine sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 6893-02-3,15785-49-6,7013-53-8
triiodothyronine

: 31135-55-4
L-Triiodothyronine sulfate

Guidance literature:: With chlorosulfonic acid; trifluoroacetic acid; at 0 ℃; for 0.166667h;
DOI:10.1002/chem.201405442

Reference yield:

: 77074-49-8
L-thyroxine sulfate

: 64192-57-0
3,3'-diiodo-L-thyronine sulfate

: 3,3'5'-triiodo-L-thyronine sulfate

: 31135-55-4
L-Triiodothyronine sulfate

Guidance literature:: With sodium tetrahydroborate; diothiothreitol; In aq. phosphate buffer; at 37 ℃; pH=7.5;
DOI:10.1002/chem.201405442

Reference yield:

: 51-48-9,24486-40-6
L-thyroxine

: 64192-57-0
3,3'-diiodo-L-thyronine sulfate

: 3,3'5'-triiodo-L-thyronine sulfate

: 31135-55-4
L-Triiodothyronine sulfate

Guidance literature:: Multi-step reaction with 2 steps

1: chlorosulfonic acid; trifluoroacetic acid / 0.17 h / 0 °C

2: sodium tetrahydroborate; diothiothreitol / aq. phosphate buffer / 37 °C / pH 7.5

With chlorosulfonic acid; sodium tetrahydroborate; trifluoroacetic acid; diothiothreitol; In aq. phosphate buffer;
DOI:10.1002/chem.201405442