1-NAPHTHYLACETIC ANHYDRIDE

Base Information

• Chemical Name: 1-NAPHTHYLACETIC ANHYDRIDE
• CAS No.: 5415-58-7
• Molecular Formula: C24H18 O3
• Molecular Weight: 354.4
• Hs Code.: 2916399090
• Mol file: 5415-58-7.mol

Synonyms:1-Naphthaleneaceticacid, anhydride (9CI); 1-Naphthaleneacetic anhydride (8CI); 1-Naphthylaceticanhydride; NSC 10202

Chemical Property of 1-NAPHTHYLACETIC ANHYDRIDE

Chemical Property:

• Vapor Pressure: 1.9E-12mmHg at 25°C
• Melting Point: 116-119 °C(lit.)
• Boiling Point: 557.1°Cat760mmHg
• Flash Point: 276.3°C
• PSA: 43.37000
• Density: 1.244g/cm³
• LogP: 4.84800
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

1-Naphthaleneaceticanhydride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-Naphthaleneacetic anhydride (cas# 5415-58-7) is a compound useful in organic synthesis.

Technology Process of 1-NAPHTHYLACETIC ANHYDRIDE

There total 3 articles about 1-NAPHTHYLACETIC ANHYDRIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

naphth-1-yl acetic acid (86-87-3) → 2-(naphthalen-1-yl)acetic anhydride (5415-58-7)

Guidance literature:

With pyridine; sodium hydrogencarbonate; 4-chloro-3-nitro-chromen-2-one; In N,N-dimethyl-formamide; at 18 - 60 ℃; for 0.3h;

DOI:10.1007/BF00471758

Reference yield:

naphthalen-1-yl-acetyl chloride (5121-00-6) → 2-(naphthalen-1-yl)acetic anhydride (5415-58-7)

Guidance literature:

With benzene;

DOI:10.1021/ja01154a130

Reference yield:

→ 2-(naphthalen-1-yl)acetic anhydride (5415-58-7)

Guidance literature:

1-Naphthoesaeure, Essigsaeureanhydrid;

upstream raw materials:

naphth-1-yl acetic acid

naphthalen-1-yl-acetyl chloride

Downstream raw materials:

(1R)-1-[N-(1-naphthylacetyl)-L-O-methyltyrosyl-L-valyl]amino-2-(4-methoxyphenyl)-ethylboronic acid

(1R)-1-[N-(1-naphthylacetyl)-L-O-methyltyrosyl-L-valyl]amino-2-phenylethylboronic acid

(1R)-1-[N-(1-naphthylacetyl)-L-O-methyltyrosyl-L-valyl]amino-3-methyl-1-butylboronic acid

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