3-Oxofriedelan-25-oic acid

Base Information

• Chemical Name: 3-Oxofriedelan-25-oic acid
• CAS No.: 32337-26-1
• Molecular Formula: C30H48O3
• Molecular Weight: 456.7
• Mol file: 32337-26-1.mol

Synonyms:3-ketofriedelan-25-oic acid;(4aR,6aR,6bR,8aS,9R,12aR,12bR,14aS,14bR)-2,2,4a,6a,8a,9,14a-Heptamethyl-10-oxo-icosahydro-picene-12b-carboxylic acid;3-oxo-D:A-friedooleanan-25-oic acid;roxburghonic acid;

Chemical Property of 3-Oxofriedelan-25-oic acid

Chemical Property:

• PSA: 54.37000
• LogP: 7.52170

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Oxofriedelan-25-oic acid

There total 5 articles about 3-Oxofriedelan-25-oic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

25-hydroxy-D:A-friedo-oleanan-3-one (74285-70-4) → 3-oxo-D:A-friedo-oleanan-25-oic acid (32337-26-1)

Guidance literature:

With chromium(VI) oxide; sulfuric acid; In acetone; at 27 ℃; for 18h;

DOI:10.1016/S0040-4039(00)87252-4

Reference yield:

C30H48O3 (160682-30-4) → 3-oxo-D:A-friedo-oleanan-25-oic acid (32337-26-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.12 g / Li / ethane-1,2-diamine / 4 h / Heating

2: 10percent CrO₃, pyridine / Ambient temperature

With pyridine; chromium(VI) oxide; lithium; In ethylenediamine;

Reference yield:

3β-acetoxy-7β,25-oxido-D:A-friedooleanane (55626-96-5) → 3-oxo-D:A-friedo-oleanan-25-oic acid (32337-26-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 0.28 g / CrO₃, AcOH / 1.5 h / Heating

2: 0.14 g / 5percent methanolic KOH / 4 h / Heating

3: 0.12 g / Li / ethane-1,2-diamine / 4 h / Heating

4: 10percent CrO₃, pyridine / Ambient temperature

With pyridine; chromium(VI) oxide; potassium hydroxide; lithium; acetic acid; In ethylenediamine;

upstream raw materials:

25-hydroxy-D:A-friedo-oleanan-3-one

3β-hydroxy-D:A-friedoolean-25-oic acid

C₃₀H₄₈O₃

3β-acetoxy-7β,25-oxido-D:A-friedooleanane

Refernces

• 1、 Weeratunga, Gamini,Kumar, Vijaya,Sultanbawa, M. Uvais S.. "D:A-Friedooleananes from Elaeodendron glaucum". . p. 1067 - 1072. Retrieved 2007/10/02.