(3S)-3aβ-Bromomethyl-2,3,3a,8b-tetrahydro-3α,6,8bβ-trimethyl-1H-cyclopenta[b]benzofuran

Base Information

• Chemical Name: (3S)-3aβ-Bromomethyl-2,3,3a,8b-tetrahydro-3α,6,8bβ-trimethyl-1H-cyclopenta[b]benzofuran
• CAS No.: 68773-08-0
• Molecular Formula: C₁₅H₁₉BrO
• Molecular Weight: 295.219
• Mol file: 68773-08-0.mol

Synonyms:1H-Cyclopenta[b]benzofuran,3a-(bromomethyl)-2,3,3a,8b-tetrahydro-3,6,8b-trimethyl-, [3S-(3a,3ab,8bb)]-; Isoaplysin

Chemical Property of (3S)-3aβ-Bromomethyl-2,3,3a,8b-tetrahydro-3α,6,8bβ-trimethyl-1H-cyclopenta[b]benzofuran

Chemical Property:

• PSA: 9.23000
• LogP: 4.20870

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3S)-3aβ-Bromomethyl-2,3,3a,8b-tetrahydro-3α,6,8bβ-trimethyl-1H-cyclopenta[b]benzofuran

There total 2 articles about (3S)-3aβ-Bromomethyl-2,3,3a,8b-tetrahydro-3α,6,8bβ-trimethyl-1H-cyclopenta[b]benzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

debromoaplysinol → isoaplysin (68773-08-0)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In benzene; for 1h; Heating;

DOI:10.1246/bcsj.59.3981

Reference yield:

isolaurenisol → isoaplysin (68773-08-0)

Guidance literature:

With trifluoroacetic acid; for 0.5h; Ambient temperature;

DOI:10.1016/S0031-9422(00)84948-1

Reference yield:

isoaplysin (68773-08-0) → (-)-Debromoaplysin (23444-68-0)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 5h; Heating;

DOI:10.1246/bcsj.59.3981

Downstream raw materials:

(-)-Debromoaplysin

Refernces

• 1、 Suzuki, Minoru,Kurata, Kazuya,Kurosawa, Etsuro. "The Structure of Isoaplysin, a Brominated Rearranged Cuparane-Type Sesquiterpenoid from the Red Alga Laurencia okamurai Yamada". . p. 3981 - 3982. Retrieved 2007/10/02.