Diazaquinomycin A

Base Information

• Chemical Name: Diazaquinomycin A
• CAS No.: 87614-40-2
• Molecular Formula: C₂₀H₂₂N₂O₄
• Molecular Weight: 354.406
• Hs Code.: 2933990090
• NSC Number: 626554
• DSSTox Substance ID: DTXSID40236523
• Nikkaji Number: J51.514K
• Wikidata: Q77567144
• Metabolomics Workbench ID: 103507
• ChEMBL ID: CHEMBL2004796
• Mol file: 87614-40-2.mol

Synonyms:antibiotic OM 704A;diazaquinomicin A;diazaquinomycin A;OM 704 A;OM 704A;OM-704 A

Chemical Property of Diazaquinomycin A

Chemical Property:

• Vapor Pressure: 1.39E-15mmHg at 25°C
• Boiling Point: 625.9°C at 760 mmHg
• Flash Point: 222.6°C
• PSA: 100.38000
• Density: 1.28g/cm³
• LogP: 3.18500
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 354.15795719
• Heavy Atom Count: 26
• Complexity: 827

Purity/Quality:

95% ^*data from raw suppliers

DIAZAQUINOMYCIN A 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC1=C(C(=O)NC2=C1C(=O)C3=C(C2=O)NC(=O)C(=C3CCC)C)C

Technology Process of Diazaquinomycin A

There total 24 articles about Diazaquinomycin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

diazaquinomycin B → diazaquinomycin A (87614-40-2)

Guidance literature:

In methanol; dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/0040-4039(88)85288-2

Reference yield: 95.0%

N,N'-(2,5-dihydroxy-1,3-phenylene)bis(2-methyl-3-oxohexanamide) (120040-68-8) → diazaquinomycin A (87614-40-2)

Guidance literature:

With hydrogenchloride; at 11 ℃; for 1.5h;

DOI:10.1016/0040-4039(88)85288-2

Reference yield: 30.0%

3,5-dimethyl-4,5-dipropyl-1,8-diazaanthracene-2,9,10-trione (203123-33-5) → diazaquinomycin A (87614-40-2)

Guidance literature:

3,5-dimethyl-4,5-dipropyl-1,8-diazaanthracene-2,9,10-trione; In trifluoroacetic acid; at 20 ℃; for 4h;

With p-toluenesulfonyl chloride; In water; acetonitrile; at 60 ℃; for 4h;

DOI:10.1016/S0040-4020(00)00371-9

upstream raw materials:

Diazaquinomycin B

N,N'-(2,5-dihydroxy-1,3-phenylene)bis(2-methyl-3-oxohexanamide)

3,7-Dimethyl-1,9-dioxy-4,6-dipropyl-pyrido[3,2-g]quinoline-5,10-dione

3,5-dimethyl-4,5-dipropyl-1,8-diazaanthracene-2,9,10-trione

Downstream raw materials:

2,8-Dimethoxy-3,7-dimethyl-4,6-dipropyl-pyrido[3,2-g]quinoline-5,10-dione