4-methoxyphenyl-(5-methyl-6-(2-(4-morpholinyl)ethyl)-6H-thieno(2,3-b)pyrrol-4-yl)phenylmethanone

Base Information

Chemical Name:4-methoxyphenyl-(5-methyl-6-(2-(4-morpholinyl)ethyl)-6H-thieno(2,3-b)pyrrol-4-yl)phenylmethanone
CAS No.:134327-81-4
Molecular Formula:C₂₁H₂₄N₂O₃S
Molecular Weight:384.499
Hs Code.:
Mol file:134327-81-4.mol

Synonyms:6H-Thieno[2,3-b]pyrrole,methanone deriv.

Suppliers and Price of 4-methoxyphenyl-(5-methyl-6-(2-(4-morpholinyl)ethyl)-6H-thieno(2,3-b)pyrrol-4-yl)phenylmethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 4-methoxyphenyl-(5-methyl-6-(2-(4-morpholinyl)ethyl)-6H-thieno(2,3-b)pyrrol-4-yl)phenylmethanone

Chemical Property:

Vapor Pressure:2.61E-12mmHg at 25°C
Melting Point:119-121 °C(Solv: methanol (67-56-1))
Boiling Point:553.9°Cat760mmHg
PKA:5.75±0.10(Predicted)
Flash Point:288.8°C
PSA：71.94000
Density:1.27g/cm³
LogP:5.18790

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-methoxyphenyl-(5-methyl-6-(2-(4-morpholinyl)ethyl)-6H-thieno(2,3-b)pyrrol-4-yl)phenylmethanone

There total 2 articles about 4-methoxyphenyl-(5-methyl-6-(2-(4-morpholinyl)ethyl)-6H-thieno(2,3-b)pyrrol-4-yl)phenylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 60143-77-3
1-(4'-methoxyphenyl)butane-1,3-dione

: 134327-81-4
(4-methoxyphenyl)-<5-methyl-6-(2-(4-morpholinyl)ethyl)-6H-thieno-<2,3-b>pyrrol-4-yl>methanon

Guidance literature:: Multi-step reaction with 3 steps

1: 36 percent / gl. acetic acid / 0.5 h / Heating

2: 28 percent / 40 percent methanolic HCl / methanol / 3 h / Heating

3: 1)NaH / 1) DMF, 1 h, 60 deg C, 2) 2 h, 75 deg C

With hydrogenchloride; sodium hydride; acetic acid; In methanol;
DOI:10.1002/ardp.19913240406

Reference yield:

: 134327-85-8
N-<3-(1-Acetyl-2-hydroxy-2-(4-methoxyphenyl)-ethenyl)-2-thienyl>-essigsaeureamid

: 134327-81-4
(4-methoxyphenyl)-<5-methyl-6-(2-(4-morpholinyl)ethyl)-6H-thieno-<2,3-b>pyrrol-4-yl>methanon

Guidance literature:: Multi-step reaction with 2 steps

1: 28 percent / 40 percent methanolic HCl / methanol / 3 h / Heating

2: 1)NaH / 1) DMF, 1 h, 60 deg C, 2) 2 h, 75 deg C

With hydrogenchloride; sodium hydride; In methanol;
DOI:10.1002/ardp.19913240406