Dihydroxythiobinupharidine

Base Information

Chemical Name:Dihydroxythiobinupharidine
CAS No.:30343-70-5
Molecular Formula:C₃₀H₄₂N₂O₄S
Molecular Weight:526.74
Hs Code.:
Mol file:30343-70-5.mol

Synonyms:Neothiobinupharidine,6,15-dihydroxy-, (6a,7S,13S,15b)-;Thionuphlutine A, 6,6'-dihydroxy- (8CI); 6,6'-Dihydroxythiobinupharidine;6,6'-Dihydroxythionuphlutine A;Dispiro[2H-quinolizine-3(4H),2'(3'H)-thiophene-4'(5'H),3''(4''H)-[2H]quinolizine]-4,4''-diol,6,6''-di-3-furanyldodecahydro-9,9''-dimethyl-, [3S-[3a(3''R*,4''S*,6''R*,9''S*,9''aR*),4b,6b,9a,9aa]]-; Nuphlein; Nuphleine

Suppliers and Price of Dihydroxythiobinupharidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
6,6′-Dihydroxythiobinupharidine ≥95% (HPLC)
1mg
$ 445.00

Total 18 raw suppliers

Chemical Property of Dihydroxythiobinupharidine

Chemical Property:

Boiling Point:667.3±55.0 °C(Predicted)
PKA:13.42±0.70(Predicted)
Density:1.30±0.1 g/cm3(Predicted)
Storage Temp.:-20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

6,6′-Dihydroxythiobinupharidine ≥95% (HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Dihydroxythiobinupharidine

There total 5 articles about Dihydroxythiobinupharidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: C₃₂H₄₀N₄O₂S

: 30343-70-5,30343-71-6,51153-11-8,58846-67-6
6,6'-dihydroxythionuphlutine B

Guidance literature:: With silver nitrate; In water; acetonitrile; at 45 ℃;
DOI:10.1002/anie.201503934

Reference yield:

: 60161-30-0
4-(furan-3-yl)-1-methyl-7-methyleneoctahydro-2H-quinolizine

: 30343-70-5,30343-71-6,51153-11-8,58846-67-6
6,6'-dihydroxythionuphlutine B

Guidance literature:: Multi-step reaction with 5 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 °C

2.1: dichloromethane / 2 h / 0 °C

3.1: acetonitrile / 3 h / 20 °C

4.1: indium(III) triflate; 2,6-bis[(3aR,8aS)-3a,8a-dihydro-8H-indeno[1,2-d]oxazolin-2-yl]pyridine / dichloromethane / 0.08 h / 20 °C / Molecular sieve

4.2: 8 h / 20 °C / Molecular sieve

5.1: silver nitrate / acetonitrile; water / 45 °C

With indium(III) triflate; 2,6-bis[(3aR,8aS)-3a,8a-dihydro-8H-indeno[1,2-d]oxazolin-2-yl]pyridine; silver nitrate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; water; acetonitrile;
DOI:10.1002/anie.201503934

Reference yield:

: C₁₅H₂₁NO₂

: 30343-70-5,30343-71-6,51153-11-8,58846-67-6
6,6'-dihydroxythionuphlutine B

Guidance literature:: Multi-step reaction with 4 steps

1.1: dichloromethane / 2 h / 0 °C

2.1: acetonitrile / 3 h / 20 °C

3.1: indium(III) triflate; 2,6-bis[(3aR,8aS)-3a,8a-dihydro-8H-indeno[1,2-d]oxazolin-2-yl]pyridine / dichloromethane / 0.08 h / 20 °C / Molecular sieve

3.2: 8 h / 20 °C / Molecular sieve

4.1: silver nitrate / acetonitrile; water / 45 °C

With indium(III) triflate; 2,6-bis[(3aR,8aS)-3a,8a-dihydro-8H-indeno[1,2-d]oxazolin-2-yl]pyridine; silver nitrate; In dichloromethane; water; acetonitrile;
DOI:10.1002/anie.201503934