O-(4-cyanophenyl) O,O-diethyl phosphorothioate

Base Information

• Chemical Name: O-(4-cyanophenyl) O,O-diethyl phosphorothioate
• CAS No.: 33841-12-2
• Molecular Formula: C11H14NO3PS
• Molecular Weight: 271.2725
• Mol file: 33841-12-2.mol

Synonyms:

Chemical Property of O-(4-cyanophenyl) O,O-diethyl phosphorothioate

Chemical Property:

• Vapor Pressure: 3.95E-05mmHg at 25°C
• Boiling Point: 352°C at 760 mmHg
• Flash Point: 166.7°C
• Density: 1.24g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of O-(4-cyanophenyl) O,O-diethyl phosphorothioate

There total 5 articles about O-(4-cyanophenyl) O,O-diethyl phosphorothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

p-cyanophenyl diethyl phosphite (70971-87-8) → O-p-cyanophenyl O,O-diethyl phosphorothioate (33841-12-2)

Guidance literature:

With sulfur; In benzene; at 100 - 110 ℃; for 30h;

Reference yield: 67.0%

diethyl phosphorochloridothioate (2524-04-1) + potassium 4-cyano-2-methylphenoxide (76211-56-8) → O-p-cyanophenyl O,O-diethyl phosphorothioate (33841-12-2)

Guidance literature:

Reference yield:

4-cyanophenol (767-00-0) → O-p-cyanophenyl O,O-diethyl phosphorothioate (33841-12-2)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / diethyl ether / 3 h / Ambient temperature

2: 71 percent / sulfur / benzene / 30 h / 100 - 110 °C

With sulfur; triethylamine; In diethyl ether; benzene;

upstream raw materials:

p-cyanophenyl diethyl phosphite

diethyl phosphorochloridothioate

potassium 4-cyano-2-methylphenoxide

4-cyanophenol

Downstream raw materials:

sodium diethylthiophosphate

Refernces