2-Methyl-6-tridecylpiperidine

Base Information

• Chemical Name: 2-Methyl-6-tridecylpiperidine
• CAS No.: 35285-26-8
• Molecular Formula: C₁₉H₃₉N
• Molecular Weight: 281.525
• NSC Number: 177343,177342
• DSSTox Substance ID: DTXSID10954429
• Nikkaji Number: J3.087.735G
• Mol file: 35285-26-8.mol

Synonyms:2-Methyl-6-tridecylpiperidine;METHYLTRIDECYLPIPERIDINE, TRANS;32778-77-1;NSC177342;NSC 177343;Piperidine, 2-methyl-6-tridecyl-, (2R-trans)-;SCHEMBL3217495;DTXSID10954429;AJAXYTHTWGIEHL-UHFFFAOYSA-N;METHYLTRODECYLPIPERIDINE, CIS;NSC177343;NSC-177342;NSC-177343;35285-26-8

Chemical Property of 2-Methyl-6-tridecylpiperidine

Chemical Property:

• Vapor Pressure: 4.57E-05mmHg at 25°C
• Boiling Point: 349.8°Cat760mmHg
• Flash Point: 171.2°C
• Density: 0.824g/cm³
• XLogP3: 7.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 12
• Exact Mass: 281.308250248
• Heavy Atom Count: 20
• Complexity: 202

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCC1CCCC(N1)C

Technology Process of 2-Methyl-6-tridecylpiperidine

There total 33 articles about 2-Methyl-6-tridecylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N-Boc-2(R)-methyl-6(R)-tridecylpiperidine (136904-85-3) → solenopsin B (32778-77-1,35285-26-8)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 6h;

DOI:10.1002/jhet.5570450112

Reference yield: 89.0%

2-methyl-6-tridecylpyridine → cis-2-methyl-6-tridecylpiperidine (83019-09-4,35285-26-8)

Guidance literature:

With 10% Pt/activated carbon; hydrogen; acetic acid; In methanol; for 72h; under 3620.13 Torr; optical yield given as %de;

DOI:10.1016/j.tetasy.2012.05.005

Reference yield: 85.0%

N-Boc-2(S)-methyl-6(S)-tridecylpiperidine (1010076-12-6) → (2S,6S)-solenopsin B (159404-03-2,35285-26-8)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 6h;

DOI:10.1002/jhet.5570450112

upstream raw materials:

N-Boc-2(S)-methyl-6(S)-tridecylpiperidine

N-tosyl solenopsin B

N-Boc-2(R)-methyl-6(R)-tridecylpiperidine

(R)-nonadec-1-en-6-yl azide

Downstream raw materials:

N-tosyl solenopsin B

Refernces

• 1、 Bandara Herath,Dhammika Nanayakkara. "Synthesis of enantiomerically pure fire ant venom alkaloids: Solenopsins and isosolenopsins A, B and C". . p. 129 - 136. Retrieved 2008/09/20.
• 2、 Solladie, Guy,Huser, Nathalie. "Asymmetric synthesis of solenopsins A, B and C". . p. 153 - 156. Retrieved 2007/10/02.