D-Glucitol, 1,4-diamino-1,4-dideoxy-3-O-(4-deoxy-4-((1-oxopropyl)amino)-alpha-D-glucopyranosyl)-

Base Information

Chemical Name:D-Glucitol, 1,4-diamino-1,4-dideoxy-3-O-(4-deoxy-4-((1-oxopropyl)amino)-alpha-D-glucopyranosyl)-
CAS No.:60534-70-5
Molecular Formula:C₁₅H₃₁N₃O₉
Molecular Weight:397.426
Hs Code.:
DSSTox Substance ID:DTXSID80975949
Wikidata:Q82960680

Synonyms:Sorbistin A1;Antibiotic gla1;Antibiotic P 2563-I;Antibiotic BN 186A;Antibiotic P 2563P;Antibiotic BU 2183A;GL A1;P 2563-I;60534-70-5;D-Glucitol, 1,4-diamino-1,4-dideoxy-3-O-(4-deoxy-4-((1-oxopropyl)amino)-alpha-D-glucopyranosyl)-;DTXSID80975949;C15H31N3O9;C15-H31-N3-O9;LS-71367;1,4-Diamino-1,4-dideoxy-3-O-{4-deoxy-4-[(1-hydroxypropylidene)amino]hexopyranosyl}hexitol

Suppliers and Price of D-Glucitol, 1,4-diamino-1,4-dideoxy-3-O-(4-deoxy-4-((1-oxopropyl)amino)-alpha-D-glucopyranosyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of D-Glucitol, 1,4-diamino-1,4-dideoxy-3-O-(4-deoxy-4-((1-oxopropyl)amino)-alpha-D-glucopyranosyl)-

Chemical Property:

Vapor Pressure:7.94E-31mmHg at 25°C
Boiling Point:815.8°C at 760 mmHg
Flash Point:447.2°C
PSA：224.47000
Density:1.46g/cm³
LogP:-3.05360
XLogP3:-5.3
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:10
Exact Mass:397.20602957
Heavy Atom Count:27
Complexity:458

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)NC1C(OC(C(C1O)O)OC(C(CN)O)C(C(CO)O)N)CO

Technology Process of D-Glucitol, 1,4-diamino-1,4-dideoxy-3-O-(4-deoxy-4-((1-oxopropyl)amino)-alpha-D-glucopyranosyl)-

There total 29 articles about D-Glucitol, 1,4-diamino-1,4-dideoxy-3-O-(4-deoxy-4-((1-oxopropyl)amino)-alpha-D-glucopyranosyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 77594-16-2
N-{(2S,3R,4S,5R,6R)-6-[(1S,2R,3S)-2-Amino-1-((S)-2-amino-1-hydroxy-ethyl)-3,4-dihydroxy-butoxy]-4,5-bis-benzyloxy-2-hydroxymethyl-tetrahydro-pyran-3-yl}-propionamide

: 60534-70-5
sorbistin A₁

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 6h; Yield given;
DOI:10.1016/0040-4020(80)80148-7

Reference yield:

: 64552-06-3
methyl 4,6-O-benzylidene-α-D-galactopyranoside

: 60534-70-5
sorbistin A₁

Guidance literature:: Multi-step reaction with 13 steps

1: 1.) NaH / 1.) DMF, 1.5 h, 20 deg C, 2.) 3 h, 20 deg C

2: 80 percent AcOH aq. / 3 h / 80 - 85 °C

3: pyridine / 20 h / 20 °C

4: 91 percent / pyridine / 1.) -5 - 0 deg C, 10 min, 2.) 17 h, 20 deg C

5: 93.4 percent / sodium azide / dimethylformamide / 25 h / 140 - 160 °C

6: 95 percent / 80 percent AcOH aq. / 3 h / 80 °C

7: 98 percent / pyridine / 15 h / 20 °C

8: 75.5 percent / conc. H₂SO₄ / 0.5 h / 20 °C

9: 22.4 percent / HCl / CH₂Cl₂ / 1.) -5 deg C, 2.) 20 deg C, 15 h

10: 1.) Et₄NCl, Et(i-Pr)2N, 2) 80 percent AcOH aq. / 1.) ClCH₂ClCH₂, reflux, 3 d, 2.) 20 deg C, 2 d

11: H₂ / Lindlar / ethanol / 4 h / 50 °C

12: AcOH / ethanol / 15 h / 20 °C

13: H₂, 0.1 N HCl / 10 percent Pd-C / ethanol / 6 h / 20 °C

With pyridine; hydrogenchloride; sodium azide; sulfuric acid; tetraethylammonium chloride; hydrogen; sodium hydride; acetic acid; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; Lindlar's catalyst; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/0040-4020(80)80148-7

Reference yield:

: 29388-46-3
methyl 2,3-di-O-benzyl-α-D-galactopyranoside

: 60534-70-5
sorbistin A₁

Guidance literature:: Multi-step reaction with 11 steps

1: pyridine / 20 h / 20 °C

2: 91 percent / pyridine / 1.) -5 - 0 deg C, 10 min, 2.) 17 h, 20 deg C

3: 93.4 percent / sodium azide / dimethylformamide / 25 h / 140 - 160 °C

4: 95 percent / 80 percent AcOH aq. / 3 h / 80 °C

5: 98 percent / pyridine / 15 h / 20 °C

6: 75.5 percent / conc. H₂SO₄ / 0.5 h / 20 °C

7: 22.4 percent / HCl / CH₂Cl₂ / 1.) -5 deg C, 2.) 20 deg C, 15 h

8: 1.) Et₄NCl, Et(i-Pr)2N, 2) 80 percent AcOH aq. / 1.) ClCH₂ClCH₂, reflux, 3 d, 2.) 20 deg C, 2 d

9: H₂ / Lindlar / ethanol / 4 h / 50 °C

10: AcOH / ethanol / 15 h / 20 °C

11: H₂, 0.1 N HCl / 10 percent Pd-C / ethanol / 6 h / 20 °C

With pyridine; hydrogenchloride; sodium azide; sulfuric acid; tetraethylammonium chloride; hydrogen; acetic acid; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; Lindlar's catalyst; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/0040-4020(80)80148-7