1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-phenylmethylthiopropyl)piperazine

Base Information

Chemical Name:1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-phenylmethylthiopropyl)piperazine
CAS No.:143759-79-9
Molecular Formula:C27H30 F2 N2 O S
Molecular Weight:468.6017
Hs Code.:
DSSTox Substance ID:DTXSID30932027

Synonyms:1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-phenylmethylthiopropyl)piperazine;1-Piperazineethanol, 4-(bis(4-fluorophenyl)methyl)-alpha-(((phenylmethyl)thio)methyl)-;4-(Bis(4-fluorophenyl)methyl)-alpha-(((phenylmethyl)thio)methyl)-1-piperazineethanol;143759-79-9;C27H30F2N2OS;SCHEMBL9142375;DTXSID30932027;C27-H30-F2-N2-O-S;LS-112122;1-(Benzylsulfanyl)-3-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}propan-2-ol

Suppliers and Price of 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-phenylmethylthiopropyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-phenylmethylthiopropyl)piperazine

Chemical Property:

Vapor Pressure:4.92E-15mmHg at 25°C
Boiling Point:595.6°C at 760 mmHg
Flash Point:314°C
Density:1.225g/cm³
XLogP3:5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:468.20469108
Heavy Atom Count:33
Complexity:518

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CC(CSCC2=CC=CC=C2)O)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F

Technology Process of 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-phenylmethylthiopropyl)piperazine

There total 2 articles about 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-phenylmethylthiopropyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 20256-77-3
2-(benzylsulfanylmethyl)oxirane

: 27469-60-9
1-(4-fluorophenyl)methyl-piperazine

: 143759-79-9
1-benzylsulfanyl-3-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}propan-2-ol

Guidance literature:: 2-(benzylsulfanylmethyl)oxirane; 1-(4-fluorophenyl)methyl-piperazine; With aluminium(III) triflate; In toluene; at 70 ℃; for 5h;

With sodium hydrogencarbonate; In water; toluene; regioselective reaction;
DOI:10.1021/jo9020437