1,2,3,4-Tetrahydronaphthalen-2-ylmethanol

Base Information

• Chemical Name: 1,2,3,4-Tetrahydronaphthalen-2-ylmethanol
• CAS No.: 6947-15-5
• Molecular Formula: C11H14O
• Molecular Weight: 162.232
• European Community (EC) Number: 889-763-6
• NSC Number: 56583
• Nikkaji Number: J1.276.862A
• Mol file: 6947-15-5.mol

Synonyms:1,2,3,4-tetrahydronaphthalen-2-ylmethanol;6947-15-5;(1,2,3,4-Tetrahydronaphthalen-2-yl)methanol;NSC56583;SCHEMBL1689627;WWPWWAHQDTYCPM-UHFFFAOYSA-N;NSC-56583;AKOS014316360;1,2,3,4-tetrahydro-2-naphthalenylmethanol;CS-0237848;2-Hydroxymethyl-1,2,3,4-tetrahydronaphthalene;EN300-187509;(1,2,3,4-Tetrahydro-naphthalen-2-yl)-methanol;2-(Hydroxymethyl)-1,2,3,4-tetrahydronaphthalene

Chemical Property of 1,2,3,4-Tetrahydronaphthalen-2-ylmethanol

Chemical Property:

• Vapor Pressure: 0.00126mmHg at 25°C
• Boiling Point: 286.1°C at 760 mmHg
• Flash Point: 129.7°C
• Density: 1.047g/cm³
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 162.104465066
• Heavy Atom Count: 12
• Complexity: 144

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=CC=CC=C2CC1CO

Technology Process of 1,2,3,4-Tetrahydronaphthalen-2-ylmethanol

There total 26 articles about 1,2,3,4-Tetrahydronaphthalen-2-ylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

Na2 SO4.box-solid.10H2 O + 1,2,3,4-tetrahydro-2-naphthoic acid (53440-12-3) → 1,2,3,4-tetrahydro-2-naphthalene methanol (6947-15-5)

Guidance literature:

With LiAlH₄; In tetrahydrofuran;

Reference yield: 98.8%

Na2 SO4 *10H2 O + 1,2,3,4-tetrahydro-2-naphthoic acid (53440-12-3) → 1,2,3,4-tetrahydro-2-naphthalene methanol (6947-15-5)

Guidance literature:

With LiAlH₄; In tetrahydrofuran;

Reference yield: 78.0%

methyl 1,2,3,4-tetrahydronaphthalene-2-carboxylate (39246-30-5) → 1,2,3,4-tetrahydro-2-naphthalene methanol (6947-15-5)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Ambient temperature;

upstream raw materials:

4a,5,6,10b-tetrahydro-4H-naphtho[1,2-d][1,3]dioxane

methyl 1,2,3,4-tetrahydronaphthalene-2-carboxylate

1,2,3,4-tetrahydronaphthalene-carboxylic acid ethyl ester

(1,2-Dihydro-[2]naphthyl)-methanol

Downstream raw materials:

1,2,3,4-tetrahydronaphthalene-2-carboxaldehyde

naphthalene

2-Methylnaphthalene

2-(2-bromoethyl)naphthalene

Refernces

• 1、 -. "NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF". Paragraph 00196. . Retrieved 2020/12/01.
• 2、 Maeta, Naoya,Kamiya, Hidehiro,Okada, Yohei. "Probing Intramolecular Electron Transfer in Redox Tag Processes". . p. 8519 - 8522. Retrieved 2019/11/20.