Benzyloxycarbonyl-phenylalanyl-dehydrophenylalanine

Base Information

Chemical Name:Benzyloxycarbonyl-phenylalanyl-dehydrophenylalanine
CAS No.:88463-10-9
Molecular Formula:C26H24 N2 O5
Molecular Weight:444.47916
Hs Code.:
Mol file:88463-10-9.mol

Synonyms:benzyloxycarbonyl-phenylalanyl-dehydrophenylalanine;Z-Phe-(Z)-deltaPhe

Suppliers and Price of Benzyloxycarbonyl-phenylalanyl-dehydrophenylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of Benzyloxycarbonyl-phenylalanyl-dehydrophenylalanine

Chemical Property:

Vapor Pressure:2.12E-22mmHg at 25°C
Boiling Point:730.5°C at 760 mmHg
Flash Point:395.6°C
PSA：111.71000
Density:1.279g/cm³
LogP:4.81070
XLogP3:4.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:444.16852187
Heavy Atom Count:33
Complexity:674

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)NC(=CC2=CC=CC=C2)C(=O)O)NC(=O)OCC3=CC=CC=C3
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H](C(=O)N/C(=C/C2=CC=CC=C2)/C(=O)O)NC(=O)OCC3=CC=CC=C3

Technology Process of Benzyloxycarbonyl-phenylalanyl-dehydrophenylalanine

There total 1 articles about Benzyloxycarbonyl-phenylalanyl-dehydrophenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 156-06-9
2-oxo-3-(phenyl)propionic acid

: 5241-56-5,17324-88-8,53562-23-5,4801-80-3
benzyl [(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamate

: 88463-10-9
Cbz-Phe-ΔPhe-OH

Guidance literature:: toluene-4-sulfonic acid; In benzene; for 6h; Heating;

Reference yield: 61.0%

: 88463-10-9
Cbz-Phe-ΔPhe-OH

: H-Sar-Leu-Met-NH₂ hydrochloride

: 112059-17-3
Cbz-Phe-ΔPhe-Sar-Leu-Met-NH2

Guidance literature:: With triethylamine; 2`,3`-dideoxycytidine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 24h;

Reference yield:

: 88463-10-9
Cbz-Phe-ΔPhe-OH

: Glp-Phe-ΔPhe-His-Leu-Met-NH2

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) N-methylmorpholine, isobutylchloroformate, 2.) N-methylmorpholine / 1.) DMF, 15 deg C, 10 min, 2.) DMF, from -15 deg C to RT, 20 h

2: 90 percent / HBr / acetic acid / 1 h / Ambient temperature

3: 1.) N-methylmorpholine, isobutylchloroformate, 2.) N-methylmorpholine / 1.) DMF, -15 deg C, 10 min, 2.) DMF, from -15 deg C to RT, 20 h

With 4-methyl-morpholine; hydrogen bromide; isobutyl chloroformate; In acetic acid;