11-Morpholino-11-phenyl-6,11-dihydrodibenzo(b,e)thiepin

Base Information

Chemical Name:11-Morpholino-11-phenyl-6,11-dihydrodibenzo(b,e)thiepin
CAS No.:84964-41-0
Molecular Formula:C₂₄H₂₃NOS
Molecular Weight:373.519
Hs Code.:2934999090
DSSTox Substance ID:DTXSID201005291
Mol file:84964-41-0.mol

Synonyms:84964-41-0;BRN 4559955;11-Morpholino-11-phenyl-6,11-dihydrodibenzo(b,e)thiepin;Dibenzo(b,e)thiepin, 6,11-dihydro-11-phenyl-11-morpholino-;Morpholine, 4-(6,11-dihydro-11-phenyldibenzo(b,e)thiepin-11-yl)-;C24H23NOS;DTXSID201005291;C24-H23-N-O-S;LS-92723;4-(11-Phenyl-6,11-dihydrodibenzo[b,e]thiepin-11-yl)morpholine

Suppliers and Price of 11-Morpholino-11-phenyl-6,11-dihydrodibenzo(b,e)thiepin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
11-MORPHOLINO-11-PHENYL-6,11-DIHYDRODIBENZO(B,E)THIEPIN 95.00%
5MG
$ 504.60

Total 3 raw suppliers

Chemical Property of 11-Morpholino-11-phenyl-6,11-dihydrodibenzo(b,e)thiepin

Chemical Property:

Vapor Pressure:1.18E-09mmHg at 25°C
Boiling Point:487.5°C at 760 mmHg
Flash Point:248.6°C
PSA：37.77000
Density:1.212g/cm³
LogP:4.85430
XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:373.15003553
Heavy Atom Count:27
Complexity:487

Purity/Quality:: 11-MORPHOLINO-11-PHENYL-6,11-DIHYDRODIBENZO(B,E)THIEPIN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2(C3=CC=CC=C3CSC4=CC=CC=C42)C5=CC=CC=C5

Technology Process of 11-Morpholino-11-phenyl-6,11-dihydrodibenzo(b,e)thiepin

There total 4 articles about 11-Morpholino-11-phenyl-6,11-dihydrodibenzo(b,e)thiepin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 110-91-8,99108-56-2
morpholine

: 68276-24-4
11-chloro-11-phenyl-6,11-dihydro-dibenzo[b,e]thiepine

: 84964-41-0
11-Morpholino-11-phenyl-6,11-dihydrodibenzothiepin

Guidance literature:: In chloroform; for 13h; Heating;
DOI:10.1135/cccc19823094

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 84964-41-0
11-Morpholino-11-phenyl-6,11-dihydrodibenzothiepin

Guidance literature:: Multi-step reaction with 3 steps

1: 1) Mg / 1) ether, reflux; ether/benzene, reflux, 4 h

2: 91 percent / SOCl₂ / CH₂Cl₂ / 3 h / Heating

3: 55 percent / CHCl₃ / 13 h / Heating

With thionyl chloride; magnesium; In dichloromethane; chloroform;
DOI:10.1135/cccc19823094

Reference yield:

: 68276-30-2
11-Phenyl-6,11-dihydrodibenzothiepin-11-ol

: 84964-41-0
11-Morpholino-11-phenyl-6,11-dihydrodibenzothiepin

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / SOCl₂ / CH₂Cl₂ / 3 h / Heating

2: 55 percent / CHCl₃ / 13 h / Heating

With thionyl chloride; In dichloromethane; chloroform;
DOI:10.1135/cccc19823094