1-Formylisoquinoline thiosemicarbazone

Base Information

Chemical Name:1-Formylisoquinoline thiosemicarbazone
CAS No.:2365-26-6
Molecular Formula:C₁₁H₁₀N₄S
Molecular Weight:230.293
Hs Code.:2933990090
NSC Number:162700
Nikkaji Number:J86.377G
ChEMBL ID:CHEMBL1976175
Mol file:2365-26-6.mol

Synonyms:1-formylisoquinoline thiosemicarbazone;1-formylisoquinoline thiosemicarbazone, (E)-isomer;1-formylisoquinoline thiosemicarbazone, (Z)-isomer;IQ-1-CTS;isoquinoline-1-carboxaldehyde thiosemicarbazone

Suppliers and Price of 1-Formylisoquinoline thiosemicarbazone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
IQ 1
10mg
$ 446.00

Usbiological
IQ-1
1mg
$ 363.00

Tocris
IQ1 ≥99%(HPLC)
10
$ 189.00

Sigma-Aldrich
IQ-1 ≥95% (HPLC)
25 mg
$ 349.00

Sigma-Aldrich
IQ-1 ≥95% (HPLC)
5 mg
$ 88.80

American Custom Chemicals Corporation
1-FORMYLISOQUINOLINE THIOSEMICARBAZONE 95.00%
5MG
$ 504.11

Total 7 raw suppliers

Chemical Property of 1-Formylisoquinoline thiosemicarbazone

Chemical Property:

Vapor Pressure:3.4E-08mmHg at 25°C
Refractive Index:1.5500 (estimate)
Boiling Point:447.3°Cat760mmHg
Flash Point:224.3°C
PSA：95.39000
Density:1.33g/cm³
LogP:2.49310
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:230.06261751
Heavy Atom Count:16
Complexity:279

Purity/Quality:

99%, ^*data from raw suppliers

IQ 1 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CN=C2C=NNC(=S)N
Isomeric SMILES:C1=CC=C2C(=C1)C=CN=C2/C=N\NC(=S)N
Uses IQ 1 disrupts Wnt signaling. IQ-1 in conjunction with Wnt3a has been shown to be sufficient to maintain murine embryonic stem cell proliferation in the absence of serum. Binds to the PR72/PR130 subunit of protein phosphatase PP2A preventing β-catenin from switching co-activator usage from CBP to p300 leading to an increase in β-catenin/CBP-driven transcription at the expense of β-catenin/p300-driven transcription.

Technology Process of 1-Formylisoquinoline thiosemicarbazone

There total 1 articles about 1-Formylisoquinoline thiosemicarbazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: